Hemorrhagic symptoms occur in _________% of cases.
5 diseases that cause similar symptoms.
malaria, typhoid fever, meningococcemia, Lassa fever and other bacterial infections like pneumonia
Early symptoms progress to...
hypovolemic shock, multi-organ failure, hemorrhagic disease, death
Non-fatal cases improve ___ days after symptoms onset.
T/F - Fatal disease associated with more severe early symptoms.
T/F - Fatality rates of 70% have been historically reported in rural Africa.
High or low? - Platelets? WBCs? AST? ALT? Neutrophils?
low, low, high, low, high
T/F - Laboratory findings include thrombocytopenia, leukopenia --> neutrophilia, elevation of AST greater than ALT, electrolyte abnormalities from fluid shifts, PT and PTT prolonged thus coagulation, proteinuria and increased cretinine due to kidney shut down.
First ___ up then ___ up, as in all infections.
ELISA is ____ but not ____.
specific but not sensitive
RT-PCR and ELISA (for IgM and IgG)
IgM stays up for ___ months. IgG stays up for ___ years.