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Wider's Prostate

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jahen86's version from 2015-07-12 00:10

PSA

Question Answer
protein cleaved by PSA?seminogelin
half life of PSA2-3 days
conditions that elevate PSABPH, PCa, age, inflammation/infection, trauma/manipulation
conditions that reduce PSA5a-reductase inhibitors, low-T/androgen deprivation
HD effect on PSA?does not affect PSA, but DOES affect free PSA
PSA velocity calc?at least 3 values separated by at least 6mo time
PSAV indicating PCa?if PSA<4.0, then PSAV>.35ng/ml/yr; if PSA>4.0 then PSAV>.75ng/ml/hr
PSAD indicating PCa?>0.15ng/ml/cc
%free PSA indicating >50% chance of PCa?<10%
PSADT in local v systemic recurrence?short (<6mo) a/w systemic, long (>1yr) a/w local recurrence
memorize

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