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Weight Loss Drugs MOA

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dmreid2644's version from 2015-05-01 12:07

Section

Question Answer
Orlistatstop fat absorption
Phentermineincrease NE in the hypothalamus
Phentermine/Topirimateincrease NE in the hypothalmus and taste adversion/increase energy expenditure
Lorcaserin5HT 2c agonist
Bupropion/Naltrexoneactivation of POMC neurons to increase satiety and inhibtion of (-) feedback of b-endorphin to maintain satiety effect of the bupropion
LiraglutideGLP-1 analog - decrease GI motility/increase satiety
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