Create
Learn
Share

Viro - Bovine & Sm Rumis Review

rename
isabellepjk's version from 2017-11-03 15:31

Check yo'self before you wreck yo'self

Question Answer
What are some differential diagnoses for BVD?Depending on the presentation, differential diagnoses may include FMD, Malignant Catarrhal Fever, & respiratory tract viral diseases.
Death from myocarditis in calves is from?FMD
Abortion comes from fever, not from virus itselfFMD
7 serotypesFMD (they are: SAT1, SAT2, SAT3, asia1 & O, C, A)
Shedding before clinical signsFMD - PICORNA
Dz that can cause lameness in pigsFMD (if your foot is in your mouth, youre gonna have trouble walking)
Long distance airborne xmissionFMD
Ddx for FMD?Vesicular Stomatitis, enterovirus, & vesicular dz in swine, visceral exanthema in swine
FMD affects who?RUMNANTS (goats, sheep, cows...) & SWINE (NOT HORSES)
What dz in what situation can lead to SCC?Bovine Papillomatosis, if it is in the presentation of the papillomas forming in the bladder & GI, & can cause "endemic hematuria". In THIS case, the usually benign papillomas can turn to SCC & be malignant
Infected through abrasionsBovine Papillomatosis
Bovine Herpes Virus 2 (BHV2)Bovine Mammillitis
Bovine Mammillitis can also look likeVesicular Stomatitis, FMD, Papillomatosis, Pseudocowpox
Latent, recrudescent, intermittent, or continuous sheddingHERPES (this was specifically said in the Bovine Mammillitis section)
Horseshoe shaped scabsPseudocowpox (a cow is a pseudo-horse(shoe) ). NOTE: these occur mostly on the mammaries (muzzle/nose of nursing calves bc of this)
ZoonoticsCoronavirus. From small rumis: Orf
scrapie
All abortion dzsBVD, IBR(Infectious Bovine Rhinotracheitis), Blue Tongue.
(FMD but only bc of the fever, not the virus truly causing it),
IPV (Infectious Pustular Vulvovaginitis),
Maedi
NakedsBovine Pap - Papovirus
Blue Tongue - Reoviridae
FMD - Picorna
Rotavirus Diarrhea - Reoviridae
BVD systemic or a specific system?SYSTEMIC
Name the magic days associated w/ BVD (& what kinda situation/type)Trans-placental movement of NONCYTOPATHIC strain of BVD into fetus--> effect depends on day.
<80 days (less than a little over 2mo), resorption.
80-125 days(little over 2mo to about 4mo), IMMUNOTOLERANCE(-->PI aka persistently infected calf).
>125days(more than 4mo), birth defects(CNS, cerebellar hypoplasia, retinal defects) & abortions
Mucosal DiseaseBVD
Cerebellar HypoplasiaCalf infected after gestational day 125 w/ the ncpBVD virus
PanleukopeniaBVD (NOT MD) in postnatal non-preggo cattle
Dxing BVD (most common? gold standard?)MOST COMMON: IHC (detects ANTIGEN, bc PI/immunotolerant calves wouldn't mount a defense to be detected!). GOLD STANDARD: virus isolation
Which strain of BVD would make a PI calf: Cytopathic or noncytopathic?Noncytopathic
Mucosal dz vs FMD? (in terms of # infected)MD = only 1 or 2 affected. FMD= MANY affected
ParamyxoviridaeENVELOPED RNA
Parainfluenza 3,
Bovine Respiratory Syncytial Disease (NOT IBR--aka i better resist the Paramyxo-trend)
SyncytiumsMalignant Catarrhal Fever,
Parainfluenza 3 infxn,
Bovine Respiratory Syncytial Disease,
Infectious Bovine Rhinotracheitis (IBR) (so MCF & all 3 resp. dzs) (malignantly crushing cells together)
Which resp dz has the biggest syncytiums?Bovine Respiratory Syncytial Dz (obv, the one w/ syncytial in the name)
Most severe resp dz?IBR (HERPS IS WAY WORSE THAN A COLD)
Bovine herpes virus 1 (BHV-1)IBR, Pustular Vaginitis (NOT MALIG CATARAHAL, THATS AHV-1)
What cellular lesions do PARAMYXOVIRIDAE resp dzs make?INTRACYTOPLASMIC & INTRANUCLEAR. & of course syncytiums, for all resp. for bovine
Are there vx for the cattle resp viruses?Yes, all 3 cattle resp viruses have vx- & for Shipping Fever too (syncytial is only in experimental stages, not sure if it counts)
Hyperemic nasal mucosaeIBR - Herpes 1
Diarrhea in calves 1 week of age, vs first few weeks after birth?Coronavirus at about 1 wk of age (& older cows too, which is weird bc the Rota is the 1 that is the first few weeks but only the first few weeks, & Corona is around 1 week but then can also affect adults), Rota if first few weeks after birth
Cattle diarrheal dzs....which have vx?BOTH Corona & Rota do. (Vx dams not calves)
Which Bovine diarrhea-causing virus affects only very young cattle, & which affects old & young?Rota = only young
Corona = old & young
Diarrhea, only moderately depressed, continue to eat, & will recover in a few daysRota
Etiological agent is the Herp?Depends.
BHV-2 = mammilitis.
BHV-1 = IBR & Infectious Pustular Vulvovaginits.
Acelaphine Herpesvirus 1 = Malignant Catarrhal Fever
Leukopenia? Lymphocytosis?Leukopenia is both BVD (mentioned in infected non-preggo non-PI adults) & in Malig. Catarrhal Fever.
Lymphocytosis is in Bovine Leukemia (I feel like I pee malignantly)
If survive, permanent ocular dzMCF (catarrhal- think cataract)
How do you reactivate latent Herpes infxns?Injxns of corticosteroids
ReoviridaeRotavirus & Blue Tongue
RetroviridaeCOMB - Caprine Arthritis-Encephalitis, Ovine Pulmonary Adenomatosis, Bovine Leukemia, Maedi,
Which dz will leave the sufferer afebrile, alert, w/ good appetite?Caprine Arthritis-Encephalitis - RETRO
Mastitis & pneumonia?Caprine Arthritis-Encephalitis
White matter lesion vs grey matter lesionWhite = Caprine Arthritis-Encephalitis
Grey = PRIONS/SCRAPIE
Milk as major transmission?Caprine Arthritis-Encephalitis (Retrovirus)
Breeds susceptible to ScrapieSuffolk & Hampshire
Ovine Progressive Pneumonia akaMaedi
Virus doesnt grow on cell cultureOvine Pulmonary Adenomatosis RETRO (doesnt grow on culture & also only histopath. lots of restrictions w/ this 1)
Pea sized nodules on lungsOvine Pulmonary Adenomatosis
ArbovirusBlue Tongue (think blue mosquitos flying around) - reoviridae
B mamm - herp 2
Maedi - retro
Segmented genomesRotavirus, Blue Tongue (REOVIRUSES)
SEMEN xmissionBVD,
Infectious Pustular Vulvovaginitis /Balanoposthitis,
Maedi (FMD was mentioned, not red txt tho)
(infected semen is almost as gross as a cow's pusy-pussy squirting diarrhea out of it onto a milk maed(maid) )
NO VXMCF - Herpes 1
Caprine Arthritis-Encephalitis - Retro
Maedi - Retro
Ovine Pulmonary Adenomatosis - Retro
Scrabies - PRION
B- Corona - TORO species
(most Retros dont have vx...Bovine Leukemia has an experimental 1 but not really mentioned)
(Malignant goats made cancer unvaccinateable)
Biting arthropods & surgical equipment are common mechanical vectorsArthropods -
Maedi (arthropods maed to make like difficult) - Retro
Blue Tongue - Reo
Mammillitis - Herpes 2

Iatrogenic
Bovine Leukemia - Retro
Maedi - Retro
Pseudocowpox - Pox
Which Retrovirus will you not use serology w/?Ovine Pulmonary Adenomatosis (only histopath)
Lots of surfactant?Ovine Pulmonary Adenomatosis (Retrovirus)
Scabby mouth akaOrf
Contagious Ecthyma/contagious Pustular dermatitis akaOrf
Vesicles/ulcersVESICLES: FMD.
ULCERS: MCF, IBR, BVD (Herpes & BVD which does like everything)
GOLD STANDARD for dx BVD?Ag ELISA
RT PCR
Cell culture/isolation
Is dx mammilitis important? Why? How?Important bc looks SIMILAR to Papillomatosis, Cowpox, Pseudocowpox, Vesicular Stomatitis & FMD. So need to dx! Done w/ EM & virus isolation
Is there a vx for Shipping Fever?YES & it is MULTIAGENT (bc many diff dzs can be underlying cause)
Cattle are a dead end hostMCF
Tropics & subtropics worldwideBlue Tongue (sippin blue drinks on the beach)
Which small animals resp dz is shed in nasal/resp secretions, & which is shed in all sorts of secretions? BOTH ARE RETROSNasal/resp = OPA.
The one shed in many is Maedi
Apply vx to scarified skin before giving birthOrf
Need to do virus isolationMCF
Dead end hosts means transmission isnt usually successfulMCF
Peracute fatal Hemorrhagic Dz in...Blue Tongue in N. America (hemorrhaging out your red white & BLUE blood)
Trade barriersFMD, Blue Tongue
Immunopathology prolongs illnessMaedi (immune system MAED IT WORSE)
Does Blue Tongue have vesicles or ulcers? Neither? What are its clin signsNeither!
HYPEREMIA
Frothing,
EDEMA OF HEAD AND NECK
CORONITIS
memorize

MINE

Question Answer
Which have HIGH morbidity and LOW mortalityFoot and Mouth - Picorna
Parainfluenza 3 - paramyxo
B. Resp, Sync dz - Paramyxo
Infectious B rhinotracheitis - Paramyxo
ORF - Pox
Blue Tongue - Reo
Which have LOW morbidity and HIGH mortalityMCF - Herpes 1 (Acepha)
Which have High Morbidity AND MortalityBovine Viral Diarrhea - Flaviv
Which are Stable in the Environment?SPECIFICALLY MENTIONED
FMD - Picorna
Rotavirus - Reo
Orf - Pox

Papoviridae because it's naked
Which are specifically mentioned as shitty in the environment?Caprine Arthritis Encep - Retro
(Most retros generally)
Also all enveloped
Which has decreased milk production as a clinical signFMD - Picorna
BVD - Flaviv
Corona - Corona
Mammillitis - Herp 2
Which have verticle Transmission?Maedi - Retro (asymptoms can give to bby)
CAE - Retro - TRANSMAM NOT PLACENTAL
BVD - Flav
Pseudocowpow - Pox
Dz swine can getFMD and BVD
Which Dz can be dz via clinical signs?B papillomatosis - Papo
Scrapie - Prion
Orf - Pox
Malignant CF - Herpes 1 (Anceph)
BVD -Flav
Rotavirus - Reo
Corona - Corona
Which are acute self LimitingPR PICS
Corona - Corona
Rota - Reo
Papillomatosis - Papo
Parainfluenza 3 - Paramyx
B. Resp Synctitial Dz - Paramyx
IBR - Herpes 1
Which can be tested with Ag ELISAFMD - Picrona
Parainfluenza 3 - Paramyx
Rotavirus - Reo
Which can be tested with AB ELISACAE - Retro
Maedi - Retro (WB more sensitive but Ab ELISA most common)
Infectious PVB - Herp 1
IBR - Herp 1
BVD IF NOT PI
Special DxOPA - histopath only
Scrapie needs monoclonal Ab
IHC for BVD is most common, Gold standard is isolation
Inclusion BodiesCytoplas = RNA = Para = Parainfluenza 3
Intranuclear = Herpes = IBR, MCF, IPVB
DNA Viruses (anything else is RNA)Herpes (E):
MCF
IBR
IPVB
Mammillitis
Pox
ORF
Pseudocowpox
Papo
Papillomatosis
Life long infectionsBovine Leukemia (Retro)
All herpes
memorize