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Type 2 and 5 Hypersensitivity

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roshanbagga's version from 2017-08-07 02:58

Section

Question Answer
erythrocyte phagocytosis - hemolysis, anemiaAutoimmune hemolytic anemia - erythrocyte membrane proteins Rh targeted
platelet phagocytosis - bleedingautoimmune thrombocytopenic purpura - platelet membrane proteins
nephritis, lung hemmorhagegoodpasture's syndrome - collagenous protein in basement membranes in kidney and lung targeted (complement and fc receptor inflammation)
hyperthyroidismTYPE 5 - grave's disease - overstimulation of TSH receptors
muscle weakness/paralysisTYPE 5 - myasthenia gravis - ACh receptor inhibited by Ab
myocarditis, arthritisrheumatic fever - streptococcal cell wall Ag, Ab cross-reacts with myocardial Ag, inflammation and macrophage activation
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