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Tuberculosis

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gotcelloskills's version from 2015-04-27 06:32

Section

Causative OrganismTransmissionDiagnosis/cultureVirulence FactorsPreventionTreatmentFeatures
Mycobacterium tuberculosisvehicle (airborne)Rapid methods plus culture; initial tests are skin testingLipids in wall, ability to stimulate strong cell-mediated immunity (CMI)Avoiding airborne M. tuberculosis, BCG vaccine in other countriesIsoniazid, rifampin, and pyrazinamide + ethambutol or streptomycin for varying lengths of time (always lengthy); if resistant, additional drugs added to regimenResponsible for nearly all TB except for some HIV-positive patients
Mycobacterium avium complexvehicle (airborne)positive blood culture; chest x-rays----Rifabutin or azithromycin given to AIDS patients at riskAzithromycin or clarithromycin plus one additional antibioticsuspect this in HIV positive patients
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