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lailay's version from 2015-09-03 23:06

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Question Answer
Tumors associated with gene:APCColorectal cancer (associated with FAP)
Tumors associated with gene: BRCA1 (2)Breast and ovarian cancer
Tumors associated with gene: BRCA2 (2)Breast and ovarian cancer
Tumors associated with gene:CPD4/SMAD4Pancreatic cancer
Tumors associated with gene: DCCColon cancer
Tumors associated with gene: MEN1MEN type 1
Tumors associated with gene: NF1NeuroFibromatosis type 1
Tumors associated with gene: NF2NeuroFibromatosis type 2
Tumors associated with gene: p16Melanoma
Tumors associated with gene: p53 Most human cancers, Li-Fraumeni syndrome
Tumors associated with gene: PTEN (3)Breast cancer, prostate cancer, endometrial cancer
Tumors associated with gene: Rb (2)Retinoblastoma, osteosarcoma
Tumors associated with gene: TSC1Tuberous sclerosis
Tumors associated with gene: TSC2Tuberous sclerosis
Tumors associated with gene: VHLvon Hippel-Lindau disease
Tumors associated with gene: WT1Wilms Tumor (nephroblastoma)
Tumors associated with gene: WT2Wilms Tumor (nephroblastoma)
Gene product:APC
Gene product: BRCA1DNA repair protein
Gene product: BRCA2DNA repair protein
Gene product: CPD4/SMAD4DPC—Deleted in Pancreatic Cancer
Gene product: DCCDCC—Deleted in Colon Cancer
Gene product: MEN1
Gene product: NF1RAS GTPase activating protein (neurofibromin)
Gene product: NF2Merlin (schwannomin) protein
Gene product: p16Cyclin-dependent kinase inhibitor 2A
Gene product: p53Transcription factor for p21, blocks G1 􏰝 S phase
Gene product: PTEN
Gene product: RbInhibits E2F; blocks G1 􏰝 S phase
Gene product: TSC1Hamartin protein
Gene product: TSC2Tuberin protein
Gene product: VHLInhibits hypoxia inducible factor 1a
Gene product: WT1
Gene product: WT2
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