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Thyroid

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jennifer12345's version from 2018-12-08 17:50

Section 1

Question Answer
T3functional unit used by all cells
T4highly protein bound, free T4 more sensitive
TSHmost sensitive test of overall thyroid function
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Section 2

Question Answer
common causes of hyperthyroidismgraves disease, subacute thyroiditis, goiter, thyroid adenomas, consuming large amounts iodine
uncommon causes of hyperthyroidismpituitary tumor, pregnancy, trophoblastic tumor, thyroid carcinoma, amiodarone-induced
causes primary hypothyroidismhashimoto thyroiditis, iatrogenic, postpartum, meds
causes secondary hypothyroidismfailure of pituitary glans to stimulate thyroid gland
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Section 3

Question Answer
Graves diseaseformation auto-antibodies & triggers production of excess thyroid hormone
Thyroiditisoverstimulation thyroid then leads to hypothyroid, follows viral illness
Toxic multi-nodular goiterinsufficient intake iodine, hyperplasia leading to excess thyroid hormone
Hashimotos thyroiditisautoimmune, antithyroid antibodies usually present (anti-TPO)
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Section 4

Question Answer
Common characteristics graves diseasediffusely enlarged thyroid, exophthalmos, pretibial myxedema
Common characteristics thyroiditissubacute: tender enlarged gland, lymphocytic: non-tended enlarged gland
Common characteristics toxic multi-nodular goitermore cardiac symptomatology (a-fib, palpitations, heart failure)
Common characteristics of hasimotos thyroiditisdiffusely enlarged, firm, finely nodular painless thyroid
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Section 5

Question Answer
Signs of hyperthyroidismnervous, restlessness, tremor, fatigue, weight loss, increased sweating, tachycardia
Signs of hypothyroidismweakness/fatigue, cold intolerance, constipation, weight gain, heavy menses, infertility, depressionx
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Section 6

Question Answer
Management hyperthyroidismradioactive iodine, propranolol, thyroidectomy
Management hypothyroidismlevothyroxine
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Section 7

Question Answer
Lab values diagnostic of hyperthyroidismlow TSH, high free T4/T3
Lab values diagnostic of hypothyroidismhigh TSH, low T4
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