Thyroid Disorders

munsele's version from 2016-06-26 03:43

Section 1

Question Answer
HypothyroidismLow T4, and high TSH
Hyperthyroidism High T4, and low TSH
S/sx hypothryoidismCold intolerance/sensitvity, dry skin, fatigue, muscle cramps, voice changes, constipation, weight gain, goiter
Most common cause of hypoHashimoto's (autoimmune, body attacks own thyroid)
Myxedema ComaLife threatening emergency cause by long term, untreated hypo
Hypo DiagnosisLow T4, high TSH. Screen pts >60yo
Hypo monitoring a fib and fractures
Hypo during PGSynthroid is Cat A, 30-50% increase in dose
Synthroid full replacement dose1.6Mcg/kg/day
Thyroid hormone effect on anticoagsIncrease effect
Thyroid hormone effect on dig, theophylline, and DM medsdecrease effects

Section 2

Question Answer
Hyperthyroidism T4 high, and TSH low
Most common cause of hyperGrave's disease
Meds that can cause hyperIodine, amiodarone, and interferons
Tx of choice for Grave's RAI-131
Why should pts take BBLsControl palpitations, tremor, and tachy
Length of time to control sx with tx1-3mo
PTU and Methimazole warningsSevere liver injury, Cat D (PTU preferred in 1st, Methimazole in 2nd and 3rd)
PTU and methimazole SEHepatitis, agranulocytosis
Preferred agent in thyroid storm PTU

Section 3

Question Answer
Iodides Potassium Iodide and Iodine Soln (Lugols) and Saturated soon of potassium iodide (SSKI or thyroshield)
Iodide MOATemporarily decrease T3 and T4 levels
S/sx of thyroid stormFever, tachy, tachypnea, dehydration, sweating, agitation, delirium, psychosis, coma