Test 3 - Chapter 24 - Myocardial Infarction & Stroke

lebohese's version from 2018-03-28 01:33


Question Answer
What is the number one cause of death in Canada?Cardiovascular disease
What causes strokes?Brain cells are deprived of oxygen or are damaged by sudden bleeding into the brain
Ischemic strokes account for 80% of all strokes and are caused by ____Oxygen deprivation
Anoxia occurs whenarteries are obstructed and is the cause of brain infarcs
Thrombotic stroke is caused by _____enlarged blood clot
Embolic stroke is caused by ____an embolus (travelling clot) or plaque that has been dislodged
Hemorrhagic stroke is caused by____bleeding in the brain
Transent Ischemic attack (TIA) also known as ___Mini-stroke
Blood supply to the brain is interrupted known asStroke
Blood supply to the heart is interrupted known asMyocardial Infarction
What is atherothrombosis?the formation of blood clots in the artery
What is athersclerosis?a build up of lipids and plaque inside of artery walls
Risk factors; Nonmodifiablesage, gender, family history
Risk factors; Modifiableslifestyle, hypertension, atrial fibrillation, high cholesterol and infection
Pharmacotherapy in 2 stepsto control the build up of lipids and plaque & to reduce the formation of blood clots
Drugs that control the rate of clot formation and clot dissolution are classified as ___antithrombotics
Antithrombotics include _____ agents that inhibit plateletsantiplatelets
Antithrombotics include _____ which lessen coagulationanticoaugulants
Antithrombotics include ____ that dissolve existing clotsthrombolytics
Platelets are activated by natural substances in the blood such as _____, _____, and _____thromboxane A2 (TXA2), thrombin, collagen
MOA of AspirinBlocks enzyme cyclooxygenase, reducing plaque formation
Aspirin inhibits prostaglandin synthesis which decreases ____thromboxane A2
MOA of Glycoprtein llb/lla inhibitorsblocks the final pathway of platelet aggregation
MOA of ticlcopidine/clopidrelinterferes with platelet adhesion and aggregation
MOA of DipyridamolInhibits platelet aggregation
Anticoaugulants; Heparin derived frompig intestines or cow lungs
Heparin is administered for treatment of ____deep vein thrombosis (DVT) // unstable angina
Warfarin is administered for to preventpulmonary embolism, thrombic and embolic stroke, atrial fibrillation
Patial Thromboplastin time (aPIT) is a test that measures_____antithrombic activity
Common ending for Thrombolytics/fibrinolytics"plase/kinase"
Thrombolytics only used in the treatment of myocardial infarction
MOA of Thrombolyticsincreased activity of plasmin
Antihyperlipidemics have a common ending of "statin"
Statins reduce ___ and ___LDL and triglyceride levels
MOA of Fibric Acid DerivativesIncrease the clearance of very low density lipoprotein (VLDL)
MOA of Bile Acid Sequestrantspromote intestinal clearance of cholesterol
___ last only a few minutes and symptoms usually resolve within 1 hrTrancient Ischemic Stroke
___ is a parenternal antiplatelet drugdipyramide
Thrombolytics must be administered within the first ___ hours after a stroke1-3
Statin drugs lower what kind of cholesterol?LDL