Create
Learn
Share

Test 1- Cholinomimetics, ChE-I's

rename
stallardm's version from 2017-01-23 15:49

Section

Question Answer
MiocholAcetylcholine, used topically for optho, 4* structure
BethanecolGI and urinary extra flow, post op urinary retintion
MuscarinePoison in mushrooms, mimics PSNS activation
Pilocarpineacts on saliva, sweat, gastric glands. Can be used topically for glaucoma and dry mouth
EdrophoniumBinds reversibly, short acting, tensilon test, can be used to reverse non-depolarizing muscle relaxants
Physostygmine3*N AchE-I, does cross BBB
Neostigmine4*N, use for MG and paralytic ileus
PyridostigmineDOC for MG due to longer action
ThiophosphatesMalathion and Parathion, irreversible, mammal inactive malathion but still toxic
Nerve gasSarin, tabun, soman, permanent inactivate AchE, antidote is pralidoxine
memorize