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Teratorgens

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klau253's version from 2017-03-26 12:50

exposure of teratogens (days post conception)

Question Answer
24anecephaly
12-40limb reduction
34transposition of great vessels
36cleft lip
42ventricular septal defect
42syndactyly (fusing digits)
84hypospadias (abnormal location of urethra in male)
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drugs associated with fetotoxic effects during T1**

Question Answer
Androgensvirilisation of female foetus
oestrogensfeminisation of male foetus
warfarinnasal hypoplasia, skeletal problems
retinoidscraniofacial, cardiovascular, CNS
Diethylstilboestroluterine lesions, transplacental carcinogen
antiepilepticsfacial defects, mental retard, neural tube
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drugs after T1

Question Answer
Antiepilepticsmental retard, autism
narcoticsneonatal resp dep
warfarinfoetal haemorrhage, CNS
antidepressantsneonatal withdrawal symptoms
Benzofloppy infant syndrome, neonatal resp dep, withdrawal
ACEIoligohydraminous, growth retardm lung and kidney hypoplasia, hypocalvaria, neonatal convulsion, hypotension, anuria
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