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Sympathetic and Parasympathetic Receptors

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kimipixu's version from 2017-10-17 20:19

Sympathetic

Question Answer
Pupil dilation (mydriasis)alpha-1
Ejaculationalpha-1
Artery constrictionalpha-1 and alpha-2
Urethral sphincter contraction (No urination)alpha-1
Decreased GI mobilityalpha-2 and beta-2
Increased renin-angiotensin system activitybeta-1
Heart rate accelerationbeta-1
Large vein dilationbeta-2
Detrusor relaxation (No urination)beta-2
Bronchial dilationbeta-2
Far-visionbeta-2
Uterus relaxationbeta-2
SweatingM
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Parasympathetic

Question Answer
Heart rate decelerationM2
Pupil constriction (miosis)M3
Near-visionM3
Artery and vein constrictionNone
Endothelium dilation (NO mediated)M3
Bronchial constrictionM3
Increased GI motilityM3
Detrusor muscle contractionM3
Sphincter relaxationM3
ErectionM3
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Mechanism of Receptor Action

Question Answer
alpha-1 receptorsGq protein resulting in increased IP3 activity and calcium release
alpha-2 receptorsGi protein resulting in decreased cAMP levels
beta-1 receptorsGs protein resulting in increased cAMP levels
beta-2 receptorsGs protein resulting in increased cAMP levels
M1 receptorsGq protein resulting in increased IP3 activity and calcium release
M2 receptors (heart)Gi protein resulting in decreased cAMP levels
M3 receptors (smooth muscle and glands)Gq protein resulting in increased IP3 activity and calcium release
Nm receptorsOpening sodium/potassium channels
Nn receptorsOpening sodium/potassium channels
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