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Step 1 Drug Side Effects By Organ System High Yield *Most Common

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zulocoke's version from 2017-09-08 20:58

Drug side effects by organ System

Skin

Question Answer Column 3
Photosensitivitysulfonamides, amiodarone, tetracycline.Pneumonic "I SAT for a PHOTO"
Lupus-Like syndromesulfonamides, hydralazine, isoniazid, procainamide, phenytoin.Pneumonic "SHIPP"
Steven-Johnson syndromePhenobarbital, ethosuximide, carbamazepine, lamotrigine, penicillins, allopurinol, sulfonamides, phenytoin."Steven-Johnson Participated in Every College Level Pentathlon And Still Practices"
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Question Answer Column 3
Facial Flushingniacin, verapamil, nifedipine, diltiazem, adenosine, vancomycinPneumonic "VANNC" Vancomycin, Adenosine, Niacin, nifedipine, Calcium channel blockers (diltiazem, verapamil)
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Cardiac

Question Answer Column 3
Coronary Vasospasmcocaine, sumatriptanPneumonic "Coronary Spasm"

Cocaine, Sumatriptan
Dilated cardsiomyopathydoxorubicin, daunorubicin, cocaine, alcohol, pregnancy, hemochromatosis, geneticPneumonic "Double D's brings RUBICIN's heart to its knees
Torsades de Pointesantiarrhythmics: (Class III K blockers) Sotalol, (Class IA Na blockers) Quinidine, Macrolides: Zithromycin, Antipsychotics: Haloperidol, Anti-Malarial: Chloroquine, Protease inhibitors(HIV): -Avir, cisapridePneumonic "Anti's twist the point" Anti-arrhythmics, Anti-biotics, Anti-psychotics, Anti-malarials, Anti-viral"
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Pulm

Question Answer Column 3
CoughACE inhibitorsCough up the Ace up your sleeve
Pulmonary fibrosisBleomycin, Amiodarone, BusulfanPneumonic Breathing Always Bad.
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Hepatobilliary

Question Answer Column 3
HepatitisIsoniazid>>Vit B6 defCuz this shit ruins everything.
Hepatic NecrosisHalothane, Acetomenophen, Valproic AcidPneumonic "HAVA dying liver"
Acute cholestatic hepatitisMacrolides: azithromycin, clarithromycin, eythromycinPneumonic "ACE=ACH"
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Question Answer Column 3
Agranulocytosismethimazole, dapsone, propylthiouracil, clozapine, carbamazepine, colchicine"My Dad's Pretty Comfy Couch Costs Agran"ulocytosis
Aplastic anemiabenzene, chloramphenicol, NSAIDs, propylthiouracil, methimazole.The AplasticaNAMias are Ben, Chuck, Nate, Pete, and Matt.
Hemolytic anemia (direct Coombs-positive)methyldopa
Hemolytic anemis in G6PD deficient ptsisoniazid, sulfonamides, primaquine, aspirin, ibuprofen, nitrofurantoin, fava beans, naphthalene, dapsone.IS PAIN For Nothing Dad?"
Gray Baby syndromeChloramphenicol
ThrombosisOral contraceptive pills (OCPs)If it should bleed it clots
ThrombocytopeniaHeparin, cimetidineTX for heparin induced thrombocytopenid is Protamine Sulfate
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Genitourinary

Question Answer Column 3
Interstitial Nephritismethicillin, NSAIDsIN the MeNs room
Hemorrhagic cystitiscyclophosphamide, ifosfamideAlkylating cancer drugs piss off the bladder (administer with mesna to prevent)
Fanconi syndromeExpired tetracyclines, Wilson's disease, Heavy Metal exposure (lead)Dead cyclines kill kidneys
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Intestinal

Question Answer Column 3
Pseudomembrane colitisclindamycin, ampicillinBeing PC just AMPS up Clinda
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MSK

Question Answer Column 3
Osteoporosiscorticosteroids, heparin, smoking, alcohol, PPIs, H2 blockers
Goutfurosemide, thiazide
Tendonitis, tendon rupture and cartilage damageflouroquinolones: cirpofloxacin, levafloxacin
Gingival hyperplasiaphenytoin, verapamilthe VP has phat gums
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Endocrine

Question Answer Column 3
Adrenocortical insufficiencyglucocorticoid withdrawalACTH down regulation
Gynecomastiaspirinolactone, THC (marijuana), alcohol (chronic), cimetidine, ketoconazole, estrogens, digitalisSTACKED
Hot Flashestamoxifen, clomipheneFemales Flash their Breasts when trying to be fertile
Diabetes insipidusLithium, demeclocyclineTx: HCTZ or amiloride
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Neuro

Question Answer Column 3
Siezuresbuproprion, imipenem/cilastatin, Isoniazid, tramadol, metoclopramide, withdrawal (benzos and ETOH)IC Bad Seizures
Tardive dyskinesiaantipsychotics, metoclopramide, ReserpineParkinsons-like symptoms
Disulfiram-like reactionmetronidazole, certain cephalosporins: (cefotetan, cefopenazone, cefamondole), procarbazine, 1st gen sulfonylureas: (tolbutamide, chlorpropamide), disulfiram
Neurotoxicity/NephrotoxicityPolymixins, cisplatin, aminoglycosidesCAP from head to pee these are bad for thee
Ototoxic/NephrotoxicAminoglycosides: (gentamicin, neomycin, tobramycin amikacin), cisplatin, loop diuretics: (furosemide, bumetanide, ethacrynic acid), vancomycin
CinchonismQuinidine (class IA antiarrythmics), Quininecinchonism is HAs, tinnitis, dizziness and vision changes
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