SN Supplements references

bethdrysdale94's version from 2017-06-03 14:36

Section 1

Question Answer
Hultman 1996: detailsmuscle Cr loading in men
Hultman 1996: methodsingested Cr in different quantities over varying time periods
Hultman 1996: resultsmuscle Cr total increased by around 20% after 6days Cr supplements (20g/day). maintained when supplement continued at 2g/day for 30days. absence of continued supplement declined back to pre-supp conc. 30 days later, more gradual 20% increase in muscle Cr over 28days at 3g/day
Hultman 1996: conclusionrapid Cr load 20g for 6d can be maintained with 2g/day. 3g/day is likely to be as effective in longerterm

Section 2

Question Answer
Sale 2009: detailscreatine monohydrate supplementation on 24h urinary Cr and methylamine excretion
Sale 2009: methods2 trials (6wks apart). 4x5g/day creatine monohydrate for 5d. 20x1g/d for 5d. urine samples at baseline and post-supplement
Sale 2009: resultsless Cr excreted w/ 20x1g/d than 4x5g/d. suggests greater retention in the body. lower and more frequent doses of creatine monohydrate appear to further attenuate formation of methylamine

Section 3

Question Answer
Green 1996: detailsCHO ingestion on muscle Cr accumulation during Cr supplement in humans
Green 1996: methods5g Cr solution (A) or 5g Cr followed by 93g simple CHO solution 30 mins later. 4/d for 5d.
Green 1996: resultsCHO substantially increases muscle Cr accumulation during Cr feedings. appears to be insulin mediated (60% greater total Cr in B than A and decrease in urinary excretion)

Section 4

Question Answer
Casey 1996: detailsCr ingestion on performance and muscle metabolism during max ex in humans
Casey 1996: methods30 sec max isokinetic cycling bout, 20g CM/d for 5d (4x5g/day) then cycling again.
Casey 1996: results4% increase in work production (positively correlated with TCr). decreased cumulative loss of ATP after Cr (despite increase in work production). Change in PCr in type II fibres positively correlated with change in PCr degradation in this fibre type and change in total work production.
Casey 1996: conclusionresults suggest improvements in performance were mediated via improved ATP resynthesis

Section 5

Question Answer
Harris 2006: detailsabsorption and effect of oval Beta-alanine on muscle carnosine synthesis in human vastus lateralis
Harris 2006: methodsB-alanine administered as A) histidine dipeptides B) 10 C) 20 D) 40 mg/kg
Harris 2006: results-

Section 6

Question Answer
Hill 2007: detailsB-al supp on skeletal muscle carnosine and high intensity cycling capacity
Hill 2007: methodsB-al supp for 4 or 10 weeks. cycle capacity test to determine total work done at 110% max power. muscle biopsies taken.
Hill 2007: resultsmuscle carnosine increased by 60% (4 weeks) and 80% (10 weeks). total work during CCT = 13% increase following 4 weeks. 16.2% increase following 10 weeks. (carnosine initially increased in type IIa most, increased equally in type I eventually.)