benryan95's version from 2016-01-12 18:51


Question Answer
What is sarcoidosis?A multisystem granulomatous disorder of unknown cause
Where is prevalence of sarcoidosis highest?Northern Europe - 10-20/100000
What ages and gender is sarcoidosis most common?Adults aged 20-40, more common in women
What ethnicity are more frequently affected?African-caribbean
What alleles is sarcoidosis associated with?HLA-DRB1 and DQB1
What does acute sarcoidosis often present with?erythema nodosum with or without polyarthralgia, usually resolving spontaneously
What are pulmonary clinical features found in sarcoidosis?bilteral hilar lymphadenopathy, pulmonary infiltrates of fibrosis, dry cough, progressive dyspnoea, reduced exercise tolerance, chest pain
What can become enlarged in sarcoidosis?lymph nodes, liver, spleen, lacrimal and parotid glands
what electrolyte can be raised in sarcoidosis?Calcium - hypercalcaemia, hypercalciuria, renal stones
What can be given in the management of acute sarcoidosis?NSAIDs
What investigations can be carried out in sarcoidosis?BLood tests, urine, tuberculin skin test, CXR, lung function test, tissue biopsy, bronchoalveolar lavage, ultrasound, bone x-rays, CT/MRI
What % of patients with thoracic sarcoidosis resolve over 2 years?60%

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