RM Bioethics

rfwhite42's version from 2015-06-25 23:27


Question Answer
Bioethics definition the study of controversial ethical issues in biology and medicine and often is related to policies of practice and research.
ethics in researchnorms for conduct that distinguish between acceptable and unacceptable
Importance of ethical norms (5)Promote the aims of research, gain public trust, values in collaborative work, public finding and professional and institutional integrity.
General ethical principles (14) Don't memorize these, just recognize. Honesty, Objectivity, Integrity, carefulness, openness, respect, confidentiality, responsible publication, social responsibility, non-discrimination, competence, legality, care and consideration
What do all the 14 general ethical principles come down to?TRUST. people must trust that you'll do your job in an ethical manner
Non-ethical studies in historyDon't memorize, try to recognize: Tuskegee syphilis study, Minnesota malaria study, Guatemala syphilis study, Pfizer Trovan Study, World war II
Sources you may find research responsibilities (4)Processional codes, government regulations, institutional policies and procedures, personal convictions
Why should we discuss responsible conduct of research (7)Establish an environment that fosters open communication, develop a common foundation, promote best practices, share ideas, increase understanding, establish a culture of concern, seek to overcome the lack of a perceived need for guidance on the responsible conduct of research.
Research misconduct (6)Plagiarism, Fabrication, Falsification, Failure to obtain informed consent, Ghostwriting / Inappropriate authorship, suppression of information
Why may someone commit research misconduct (4): Career growth and recognition, continued and advanced funding, pressure from superiors, deadlines
Data management (3)protection (may need to look at it later), storage (don't lose, keep for 3 years), confidentiality (people's info is in that!)
Should you share preliminary data?NO
Should you share confirmed or validated data?no, keep confidential until publication is widely accepted.
Should you share published dataOnce published, it can bee shared / freely available so SHARE THAT ISH
Conflict of Interest Committeesmanage, reduce or eliminate significant financial conflicts
Financial conflicts (2)Report significant ($10,000 per year or >5%) financial conflicts before any research is undertaken. Manage, reduce, or eliminate significant financial conflicts. This is generally accomplished by disclosure to a Conflict of Interest Committee
Responsible authorship incorporates (3)Contribution, importance and corresponding author
ContributionAuthorship is generally limited to individuals who make significant contributions to the work
ImportanceAuthors are usually listed in order of importance
Corresponding authorAct on behalf of their colleagues (if there's 6 authors, one is the talker)
Codes of appropriate authorship All authors are obligated to fact check manuscripts submitted for publication, Gift / ghost authorship, Maintain study data for review after publication, Disclose conflicts of interest, Retract / explain false findings
Mentors should (3)provide equal treatment, maintain a professional atmosphere, train and educate in the responsible conduct of research.
Peer reviewthe evaluation by collegues with similar knowledge and experience
Peer review is needed for (4)grant reviews, manuscript reviews, personnel reviews, literature reviews and expert testimony
Informed consent for animalsOwner grants permission but you must disclose risks, benefits, full disclosure and ability to withdraw