Radiology-Isotopes used in medicine

vixokuxa's version from 2015-07-03 07:55

Section 1

Question Answer
Molybdenum-99(66hrs t1/2)used as the "parent" in a generator to produce Tc 99m
Technetium 99m(6hrs t1/2)used to image the heart muscle and skeleton in particular ;but also for brain,thyroid,lungs(ventilation & perfusion),liver ,spleen,kidney(structure & filtration rate),gall bladder,bone marrow,salivary and lacrimal glands,heart blood pool,infection,numerous specalized medical studies
uses of TC 99 tagged RBCs1)commonly indicated in Acute Lower Gastrointestinal Bleeding (2)Relatively sensitive and very specific imaging method for non invasive diagnosis of liver hemangioma (3)measurement of left ventricular ejection fraction. (4) Assessment of regional wall motion(left and right ventricles)
Chromium 51(28 days t1/2)used to label RBCs and quantify gastro intestinal protein loss
Cobalt 60 (10.5 months t1/2)formerly used for external beam radiotherapy
Copper 64(13 hrs t1/2)to study genetic diseasesaffecting copper metabolism Eg: Wilson's ds,Menke's ds
Dysprosium 165 (2hrs t1/2)used as an aggregated hydroxide for synovectomy treatment of arthritis
Erbium 169 (9.4 days t1/2)used for relieving arthritis pain in synovial joint
Holmium 166 (26 hrs t1/2 )being dvpd for diagnosis n treatment of liver tumours
Iodine 125 (60 days t1/2)used in cancer brachytherapy (prostate and brain ); and also diagnostically to evaluate the filtration rate of kidneys and to diagnose deep vein thrombosis in the leg .It is also widely used in radio immuno assays to show the presence of hormones in tiny quantities
Iodine 131 (8 days t1/2)used in TREATING THYROID CANCER , IMAGING THYROID ;in diagnosis of abnormal liver function ,renal (kidney) blood flow and urinary tract obstruction.A STRONG GAMMA EMITTER but used for BETA THERAPY.
Iridium 192 (74 days t1/2) supplied in wire form for use as internal radiotherapy source for cancer trt
Iron 59(46 days t1/2)used in studies of iron metabolism in spleen
Lutetium 177 (6.7 days )emits just enough gammas for imaging while the beta radiation does the therapy on small (Eg. endocrine ) tumours.Its half life is long enough to allow sophisticated preparation for use.
Palladium 103 (17 days t1/2)used to make brachytherapy permanent implant seeds for early stage prostate cancer
Phosphorus 32 (14 days t1/2)used in the treatment of polycythemia vera(excess RBCs ). BETA EMITTER.
Potassium 42 (12 hrs t1/2)used for the determination of exchangeable potassium in coronary blood flow.
Rhenium 186 (3.8 days t1/2)used for pain relief in bone cancer . Beta emitter with weak gamma for imaging .
Rhenium 188 (17 hrs t1/2)used to beta irradiate coronary arteries from an angioplasty balloon
Samarium 153 (47 hrs t1/2)Sm-153 is very effective in relieving the pain of secondary cancers lodged in the bone ; sold as QUADRAMET.Also very effective in prostate and breast cancer.Beta emitter.
Selenium 75 (120 days t1/2)used as seleno methionine to study the production of digestive enzymes.
Sodium 24 (15 hrs t1/2)for study of electrolytes within the body
Strontium 89 (50 days )very effective in reducing pain of prostate and breast cancer .Beta emitter.
Xenon 133 (5 days t1/2)used for pulmonary (lung)ventilation studies
Ytterbium 169 (32 days t1/2)used for cerebrospinal fluid (CSF) studies in brain
Ytterbium 177 (1.9 hrs t1/2)Progenitor of Lutetium (Lu) -177
Yttrium 90 (64 hrs t1/2)Used for cancer brachytherapy and as silicate colloid for relieving the pain of arthritis in large synovial joints .Pure BETA EMITTER.
Radioisotopes of Caesium,Gold,Ruthenium used in Brachytherapy

Section 2