Radiology - Bone Tumors

klistu's version from 2016-03-27 19:05


Question Answer
Osseous Matrixcloud like, amorphous
Cartilage Matrixpunctate, c-shaped
Fribooseous Matrixground glass
Permeative Growthwide zone of transition
Moth eatenintermediate zone of transition
Geographic Growthshort zone of transition
Perpendicularspiculated, sunbust pattern
Onion skinrepeated insults


Question Answer
Durie Salmon System for Myeloma 1Anormal skeletal survey or single lesion, good prognosis
Durie Salmon System for Myeloma 1Bsymptomatic, less than 5 lesions
Durie Salmon System for Myeloma 2A5-20 lesions, no renal disease
Durie Salmon System for Myeloma 2B5-20 lesions, renal disease present
Durie Salmon System for Myeloma 3Amore than 20 lesions, no renal disease
Durie Salmon System for Myeloma 3Bmore than 20 lesions, renal disease present


Question Answer
Giant Cell, ABC, Parosteal Osteosarcomamost common in women
Metastasesmost common bone tumors in general
Multiple Myelomamost common primary bone tumor
Ewing's Sarcomamay have an 11/22 chromosome translocation


Question Answer
Multiple Myelomaassociated with POEMS syndrome
Nonossifying fibroma and Fibrous Dysplasiaassociated with cafe au lait spots
Enchondroma, UCBpainless and asymptomatic unless it causes fracture
Sarcomasmay be painful
Ewings Sarcomaassociated with systemic symptoms


Question Answer
Osteochondromametaphyseal and points away from the joint
UCB and nonossifying fibromamigrate away from metaphysis toward diaphysisis
Parosteal Osteosarcomaa metaphyseal surface lesion
Periosteal Osteosarcomaa diaphyseal surface lesion
Giant Cellmigrates from epiphysis to metaphysiss


Question Answer
Classic Medullary Osteosarcoma and Parosteal OsteosarcomaOsseous Matrix
Chondroblastoma and OsteochondromaCartilage Matrix
Fibrous Dysplasia and Osteofibrous DysplasiaFirbooseous Matrix


Question Answer
Pain worse at night & relieved by salicylatesOsteoid Osteoma
Rarely aggresive, pseudomalignantOsteoblastoma
Pain months before diagnosis, elevated alk phosClassic Medullary Osteosarcoma
Mass with dull, aching pain and more common in femalesParosteal Osteosarcoma
Associated with the Rule of 1sOsteosarcoma in Paget's Disease
Associated with Ollier's and Mafucci'sEnchondroma
Pain and swelling, soft masses in small tubular bones of hands and feet in 20 year oldsJuxtacortical Chondroma
Pain and joint effusions due to benign cartilage lesion of epiphysisChondroblastoma
Common tumor that creates mechanical symptoms like decreased ROM, suspected when there's growth after skeletal maturity or painOsteochondroma
Benign lesion with high local recurrenceBizarrre Parosteal Osteochondromatois (BPOP)
Do not touch lesion, associated with Jaffe-Campanacci SyndromeNonossifying Fibroma
Associated with Albright's Syndrome and Mazabraud's SyndromeFibrous Dysplasia
May mimic brown tumors pathologicallyGiant Cell Reparative Granuloma
Often an incidental finding, common benign lesion that arises at growth plate and will heal inUnicameral Bone Cyst
Painful lesion with predilection for women, often occurs in the long bones and posterior elements of the spineAneurysmal Bone Cyst
Benign fibrooseous lesion, but 10% may have malignant transformation usually an incidental finding often located in the femur Liposclerosing Myxofibrous Tumor
Common primary bone tumor, presents with pain, low grade fever, weight loss and elevated SED rateEwing's Sarcoma
Polyneuropathy, Organomegaly, Endocrine abnormalities, M proteins, Skin lesionsMultiple Myeloma
Unifocal, one organ system; noninfectious granuloma with proliferating histiocytes and eosinophils, pain and systemic symptomsEosinophilic Granuloma
Rare, locally aggressive bubbly lesion, local pain and swelling almost exclusively in the tibiaAdamantinoma


Question Answer
Radiology - solid, benign cartilage tumor; erosion and saucerization of underlying boneJuxtacortical Chondroma
Radiology - multiloculated, geographic w/sclerotic margins; no calcifications, very rare tumor often in metaphysis with predilection for the LEChondromyxoid Fibroma
Radiology - cartilage-capped bony excrescence; cap may calcify, located in metaphysis and points away from jointOsteochondroma
Radiology - lucent metaphyseal lesion with calcifications; may have sclerotic marginsChondrosarcoma
Radiology - both low grade and high grade tissues presentDedifferentiated Chondrosarcoma
Radiology - benign fibroosseous lesion of bone with ground glass matrixFibrous Dysplasia
Radiology - ground glass cortical lesion almost always in the tibiaOsteofibrous Dysplasia (Ossifying Fibroma)
Radiology - aggressive lytic lesion, no matrix, no periosteal reaction, may arise secondary to other lesions, including infarctsFibrosarcoma and MFH
Radiology - lytic lesion, no matrix, may destroy cortex, have soft tissue mass, locally aggressive, usually benign but cannot predict behavior by appearanceGiant Cell Tumor
Radiology - lucent lesions; does not break through periosteum, located in hands and feetGiant Cell Reparative Granuloma
Radiology - geographic, sclerotic margins, fluid filled medullary, fallen fragment signUnicameral Bone Cyst
Radiology - lytic, expansile lesion, blood filled cavities, blow out lesion, may destroy or markedly thin the cortex, fluid-fluid levelsAneurysmal Bone Cyst
Radiology - sclerotic borders, may have central calcification, common in calcaneusIntraosseous Lipoma
Radiology - sclerotic border, no matrix, benign lesion common in medial malleolusintraosseous Ganglion
Radiology - permeative lesion, no matrix, onion skin periosteal reaction most common in the LE in the diaphyseal or meadiaphyseal regionsEwing's Sarcoma
Radiology - punched out, cookie cutter lesionsMultiple Myeloma
Radiology - vertical striations in spine, radial spokes in the skullHemangioma
Radiology - may have sequestrum, especially in skull, may be punched out, 50% occur in skullEosinophilic Granuloma
Radiology - eccentric lobulated, bubbly lesion; periostitis rare, almost always in tibiaAdamantinoma
Radiology - reactive sclerosis with lucent nidus <1cm Osteoid Osteoma
Radiology - lucent nidus > 1.5 cmOsteoblastoma
Radiology - cloud like dense bone formation, sunburst, Codman's triangleClassic Medullary Osteosarcoma
Radiology - usually osteolytic; frequent fluid-fluid levels, known as the "Ugly"Telangiectatic Osteosarcoma
Radiology - often present in hands and feet, punctate calcified matrix, may cause scalloping or expansionEnchondroma

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