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Psychiatry

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daju89's version from 2017-05-04 17:53

Drug types

Question Answer
FluoxetineSSRI
SertralineSSRI
ParoxetineSSRI
FluvoxamineSSRI
CitalopramSSRI
EscitalopramSSRI
VenlafaxineSNRI
DuloxetineSNRI
MirtazapineNASSA
ReboxetineNARI
AmitryptalineTCA
ClomipramineTCA
ImipramineTCA
LofepramineTCA
DosulepinTCA
PhenelzineMAOI
TranylcypromineMAOI
MoclobemideRIMA
LamotrigineMood Stabilizer
ValproateMood Stabilizer
LithiumMood Stabilizer
CarbamazepineMood Stabilizer
OlanzapineAtypical antipsychotic
RisperidoneAtypical antipsychotic
QuetiapineAtypical antipsychotic
HaloperidolTypical antipsychotic
ChlorpromazineTypical antipsychotic
Flupentixol decanoateTypical antipsychotic
AripiprazoleAtypical antipsychotic
ClozapineAtypical antipsychotic
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Side effects

Question Answer
SSRINausea & vomiting, appetite & weight change, blurred vision, anxiety and agitation, insomnia, tremor, dizziness, headache, sweating
SNRIConstipation, HT and raised cholesterol, plus: Nausea & vomiting, appetite & weight change, blurred vision, anxiety and agitation, insomnia, tremor, dizziness, headache, sweating
NASSASedation, increased appetite/weight, oedema
NARIDry mouth, constipation, sweating, urinary problems, insomnia, tachycardia
TCATachycardia & arrhythmias, dry mouth, blurred vision, constipation, urinary retention, postural HT, sedation, nausea, weight gain
MAOIHT crisis (cheese reaction), postural HT, dizziness, drowsiness, insomnia, headache, blurred vision, nausea & vomiting, constipation
RIMAagitation and anxiety, sleep disturbance, nausea, hypertension
At what level does Lithium become toxic?>1.2mmol/L
LithiumEbstein's anomaly, tremor, GI effects, nausea, vomitting, polyuria, polydipsia, arrhythmias, hypothyroidism, weight gain
ValproateGI effects, nausea, vomiting, diarrhoea, liver failure, thrombocytopenia, hair loss, weight gain
CarbamazepineRash, leucopenia, hyponatraemia, ataxia, oedema, may decrease other drugs
LamotrigineSkin rashes, headache, tiredness, nausea, dizziness, insomnia, arthralgia
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Mixed psych

Question Answer
Which COMT allele increases the risk of schizophrenia in cannabis users? Val or Met?Val allele. Val-Val has highest risk.
Dopamine Hypothesis: What causes negative symptoms of schizophrenia?Dopamine underactivity in mesocortical tracts
Dopamine Hypothesis: What causes positive symptoms of schizophrenia?Excess dopamine in mesolimbic tracts
What are the EPSEs of typical antipsychotics?Tardive dyskinesia (Onset: months/years. Symptoms: Rhythmic involuntary movements of mouth, face, limbs.), Akathisia (Onset: hours/weeks. Symptoms: unpleasant restlessness & agitation.) Parkinsonism (Onset: days/weeks. Symptoms: resting tremor, rigidity, bradykinesia, shuffling gait.) Dystonia (Onset: hours/days. Symptoms: Involuntary, painful, sustained muscle spasm, e.g. torticollis (neck twist), oculogyric crisis (eyes twist up and can't look down)).
What are the non EP side effects of antipsychotics?Hyperprolactinaemia, weight gain, sedation, risk of diabetes, dyslipidaemia, anticholinergic effects, arrhythmias, seizures, neuroleptic malignant syndrome (NMS).
What are the risks of clozapine?0.7% chance of agranulocytosis. 3% chance of neutropenia.
What psychological interventions are recommended for schizophrenia?CBT, family therapy, concordance therapy, psychodynamic therapy
What psychological interventions are recommended for depression?CBT, psychodynamic therapy, interpersonal therapy
What psychological interventions are recommended for mania?CBT, psychodynamic therapy
What psychological interventions are recommended for self harm & suicideDialectical behavioural therapy, transference-focused psychotherapy, mentalization-based treatment in hospital
Name 8 features of dependencyTolerance, Compulsion/Craving, Withdrawal, Problems controlling use, Continued use despite harm, Salience/primacy, Reinstatement after abstinence, Narrowing of the repertoire
Name likely findings of blood investigations in an alcoholic dependent patientraised GGT, raised transaminases suggest hepatocellular damage, raised MCV due to B12-deficiency-induced macrocytic anaemia
What psychological interventions are recommended for substance abuse?motivational interviewing
Dysfunction in which lobe might cause contralateral visual defects?occipital
Dysfunction in which lobe might cause dyscalculia?parietal
Dysfunction in which lobe might cause lability?temporal
Dysfunction in which lobe might cause contralateral spastic hemiparesis?frontal
Dysfunction in which lobe might cause return of primative reflexes?frontal
Dysfunction in which lobe might cause expressive dysphasia?frontal
Dysfunction in which lobe might cause receptive dysphasia?temporal
Dysfunction in which lobe might cause apraxias?parietal
Dysfunction in which lobe might cause agnosias?parietal
Dysfunction in which lobe might cause contralateral sensory neglect?parietal
Name a traumatic and hypoxic cause of deliriumhead injury or burns, cardiovascular or respiratory
Name two types of infective cause of deliriumintracranial infection (e.g. encephalitis) or systemic (e.g. septicaemia)
What investigations might you use for a patient with suspected delirium?FBC, U&Es, Glucose, SaO2, CXR, Ca2+, MSU, ECG, septic screen. Also consider: LFTs, blood cultures, CT head, CSF, EEG
Name one cortical and one subcortical dementiaCortical: Alzheimers, frontotemporal dementia, Binswanger's, CJD. Subcortical: Huntington's, Parkinson's, HIV dementia complex
What is the symptom triad of normal pressure hydrocephalus?subcortical dementia, unsteady gait, urinary incontinence
Korsakoff's syndrome is caused by a deficiency of what?B1 (thiamine)
What are some Parkinson's plus syndromes?progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy
What systemic illnesses might be in your differential diagnoses for depression?hypothyroidism, hypo/hyperparathyroidism, hypoadrenalism (Addison's), hyperadrenalism (Cushing's), B12 deficiency, use of corticosteroids, SLE
What systemic illnesses might be in your differential diagnoses for anxiety?Hypoglycaemia, hyperthyroidism, phaeochromocytoma
What systemic illnesses might be in your differential diagnoses for mania?Corticosteroid use, hyperadrenalism (Cushing's), hypothyroidism (rarely: "myoxedema madness")
What systemic illnesses might be in your differential diagnoses for psychosis?Porphyria, corticosteroid use, hyperadrenalism (Cushing's), SLE
What systemic illnesses might be in your differential diagnoses for dementia?Hypoadrenalism (Addison's), B12 deficiency, hyperadrenalism (Cushing's), folate deficiency, hypothyroidism, dysparathyroidism
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