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Pharmaceutics III Exam 1

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alchemist04's version from 2016-04-01 20:21

Section

Question Answer
lipopolysaccharides, LPSpyrogen
endotoxinspyrogen
normal saline/ NSelectorolyte (0.9% sodium chloride)
0.9% sodium chlorideelectrolyte
lactated ringerselectroyltes (NaCl, KCl, CaCl2, sodium lactate)
plasma expanders6% dextran 70 in normal saline
5% dextrose (D5W)carbohydrate
10% dextrosecarbohydrate
5% dextrose (D5W) in 0.45% sodium chloridecarbohydrate
ethyl alcoholwater miscible vehicles/cosolvent
memorize

 

Question Answer
polyethylene glycol (PEG400)water miscible vehicles/cosolvent
propylene glycolwater miscible vehicles/ cosolvent
soybeansnon aqueous vehicles
sesamenon aqueous vehicles
peanutnon aqueous vehicles
cornnon aqueous vehicles
castornon aqueous vehicles
haloperidol decanoatesesame oil, IM, sustained release - injectable product in non aqueous vehicles
progesteronesesame/peanut oil, IM - injectable product in non aqueous vehicles
depo-testosteronecottonseed oil, IM, sustained release -injectable product in non aqueous vehicles
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Question Answer
benzalkonium chlorideantimicrobial/preservative
benzyl alcoholantimicrobial/preservative
chlorobutanolantimicrobial/preservative
cresolantimicrobial/preservative
metacresolantimicrobial/preservative
phenolantimicrobial/preservative
phenylmercuric nitrateantimicrobial/preservative
thimerosolantimicrobial/preservative
glycine/HCLbuffers
citric acid/sodium citratebuffers
memorize

 

Question Answer
sodium acetate/acetic acidbuffers
sodium phosphatebuffers
tromethaminebuffers
carbonatebuffers
sodium chloridetonicity agent
dextrosetonicity agent
mannitoltonicity agent
sorbitoltonicity agent
polysorbate 20 (Tween20)surfactants - solubilizing agents
polysorbate 80 (Tween80)surfactants - solubilizing agents
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Question Answer
lecithinsurfactants - solubilizing agents
cyclodextrinscomplexation - solubilizing agents
polyvinylpyrolidonecomplexation - solubilizing agents
ascorbic acidantioxidant - water soluble
sodium bisulfiteantioxidant - water soluble
sodium metabisulfiteantioxidant - water soluble
sodium sulfiteantioxidant - water soluble
butylated hydroxytoluene (BHT)antioxidant - oil
butylated hydroxyanisole (BHA)antioxidant - oil
EDTAchelating agent - binds to trace metals in solution and render them non ionizable.
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Question Answer
sodiumbasic salt
potassiumbasic salt
hydrochlorideacidic salt
sulfateacidic salt
sodium bicarbonategas form when acidic salt mixed, use sodium acetate
cephalosporinsgas form when acidic salt mixed
barbiturates buffered w carbonategas form when acidic salt mixed, avoid
HCl/NaOHpH adjustment
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Question Answer
acetate calciumsupplementation
chloride calciumsupplementation
gluconate calciumsupplementation
potassium phosphatesupplementation
sodium phosphatesupplementation
nitroglycerinabsorbing drug
human serum albuminprevent adsorption
memorize

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