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Pharmac - revise again

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medmaestro's version from 2015-11-17 17:44

Section

Pharmacology
ProdrugActive Form
FamciclovirG-Deoxypenciclovir
LevodopaDopamine
EnalaprilEnalaprilat
Alpha Methyl DopaAlpha Methyl Nor Epinephrine
DipivefrineEpinephrine
SulindacSulphide Metabolite
ProguanilCycloguanil
PrednisonePrednisolone
BacampicillinAmpicillin
Sulfasalazine5-Amino Salycilic Acid
CyclophosphamideAldophosphamide,Phosphoramide Mustard,Acrolein
FluorouracilFluoro Uridine Monophosphate
MercaptopurineMethyl Mercaptopurine Ribo Nucleotide
AcyclovirAcyclovir Triphosphate
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All Ace Inhibitors Are Prodrugs Are Prodrugs Except Captopril & Lisinopril

 

Drug Displacements:
Question Answer
Salicylates DisplaceSulphonylureas & Methotrexate
Indomethacin & Phenytoin DisplaceWarfarin
Sulfonamides & Vit K DisplaceBilirubin
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Active DrugActive Metabolite
Chloral HydrateTrichloroethanol
MorphineMorphine-6 – Glucuronide
CefotaximeDesacetyl Cefotaxime
AllopurinolAlloxanthine
ProcainamideN-Acetyl Procainamide
PrimidonePhenobarbitone,Phenylethylmalonamide
LosartanE3174
DiazepamDesmethyldiazepam,Oxazepam
DigitoxinDigoxin
ImipramineDesimipramine
AmitryptilineNortryptiline
CodeineMorphine
SpironolactoneCanrenone
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Question Answer
Potencymeasure of amount of drug needed to produce the response
Efficacymaximum effect of drug
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Drugs safe in pregnancy
Question Answer
Anti Malarial TreatmentChloroquine
Antimalarial ProphylaxisProguanil
AntihypertensiveMethyl Dopa > Hydralazine > Ccbs
AntithyroidPropylthiouracil
Anti ConvulsantPhenobarbital
Eclampsia TrtMagnesium Sulphate
Hypertensive CrisisLabetalol,Hydralazine ,NTG
UTINitrofurantoin,Ampicllin,Cephalosporins
ChlamydiaAzithromycin/Erythromycin
ATTRifampicin+Isoniazid
DMARDHydroxychloroquine
Ventricular ArrhythmiaIV Lidocaine > Quinidine
Supraventricular TachycardiaAdenosine
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Vertical transmission
Question Answer
HIVZidovudine,Nevirapine
ToxoplasmaSpiramycin
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