| Question | Answer |
|---|
| dont give what to pts on MAOI or SSRI's | tryptans or turkey |
| orange mucus | rifampin |
| MOA of SSRI vs MOA of tricyclic antidepressants | SSRI block 5HT, tricyclic antidepressants block reuptake of NE/serotonin |
| what blocks hydroxytryptamine receptors | SSRI |
| SSRI drugs | sertraline, fluoxetine, paroxetine |
| SE serotonin syndrome | SSRI sertraline, fluoxetine, paroxetine |
| SNRI | venlafaxine, duloxetine |
| pt has tachycardia and rash what drug did pt take. what is another SE | linezolid, bone marrow suppression |
| A patient being treated for atrial fibrillation with an agent that decreases the slope of Phase 0 of the pacemaker action potential developed Torsades de pointes for which he was given a drug that increases the threshold for firing of pacemaker cells. Which one of the following was the patient taking for his atrial fibrillation? a. atropine b.digoxin c.flecainide d. propranolol e.quinidine | digoxin |
| Whats the antidote for malignant hyperthermia? | Dantroline |
| main SE of tricyclic antidepressants | cardiotoxicity |
| SE of paroxetine | serotonin syndrome |
| what drug do u use for smoking sensation | duloxetine |
| drugs used for epilepsy | tricyclic antidepressants |
| benzos work by | incr FREQ of cl- channels |
| anyone on MAOIs should avoid fruit because | it increases risk for tyrosine |
| what is therapeutic index | determines safety of a drug, the higher it is the safer the durg, toxic dose/effective dose; TD/ED |
| drug that produces lupus like syndrome | procainamide |
| drug that produces butterfly rash | procainamide |
| Of the following azoles, which has these characteristics: improved water solubility allowing
for treatment of CNS infections, lowest affinity for mammalian cytochrome P450 enzymes therefore least likely to cause drug interactions, safety for use during pregnancy? | fluconazole |
| infliximab MOA, clinical use | target TNF-alpha, use CRAP-crohn's dz, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis |
| Adalimumab MOA, clinical use | target TNF-alpha, treat less CRaP..so drug with A does not tx anklyosing spondylitis |
| what is efficacy? what drug has high efficacy | maximal effect an agonist can produce, morphine |
| tx overdose of morphine | maloxone |
| which drug is stronger than morphine | 1000-sufentenil 100-fentanyl |
| inhibits transformation of inorganic iodine to organic iodine so body can't form thyroxine | propylthiouracil |
| block T4 conversion to T3 | propylthiouracil |
| propylthiouracil tx's | hyperthyroidism |
| relieves symptoms of hyperthyroid | propranolol |
| drug you would use for thyroid storm | propranolol |
| Levothyroxine MOA | thyroxine replacement-replaces normal levels of T4 and T3 (T4 is converted to T3 by deiodination in ther periphery) |
| tx for hypothyroid | levothyroxine |
| truth serum drug | scopolamine |
| Scopolamine is used for | motion sickness |
| drug that gives flu like side effects | interferon alpha |
| given to prevent flu | oseltamivir, zanamivir |
| acyclovir MOA and tx's | block DNA polymerase by chain termination, tx's herpes and VZV |
| ribavarin tx's | Hep C |
| what are the inhaled anesthetics | halothane(hepatotoxicity), nitrous oxide(contraindicated in pts w/hx of a spontaneous pneumothorax), and rest will end in flurane(methoxyflurane(nephrotoxicity), enflurane(proconvulasant), sevoflurane, isoflurane(little tendency to depress cardiac output or induce arrhythmias) |
| warfarin inhibits | Vit K |
| tx warfarin overdose with | fresh frozen plasma |
| warfarin has an effect on what pathway | extrinsic pathway and incr PT(the Ex-PresidenT went to WAR(farin) |
| A farmer gets exposed to pesticides like organophosphates (ACHase Inhibitor). How do you tx em? | atropine or pralidoxime(2PAM) ACHerase re-activator) |
| don't give atropine to what type of pts | pts with glaucoma or elderly men with BPH |
| effect of atropine | mydriasis, dry as a bone, hot as a hare, red as a beet, mad as a hatter, BLIND as a bat |
| cycloplegia | atropine |
| most drugs are zero, first, or second order | first |
| dif btw zero and first order | zero-elimination is independent of amount of drug, first order-elimination is proportional to amount of drug |
| drugs that exhibit zero order | PEA phenytoin, ethanol, aspirin |
| Longest acting ester | chloroprocaine > procaine |
| Acetominophen OD | liver toxic |
| longest acting amide | bupivicaine> mepivacine >prilocaine |
| local anesthetic you cant use in children | mepivacaine |
| memorize |
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quickster2008's
version from
2015-09-17 02:39
