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Pharm WCVM exam1 pt 3

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iqemallios's version from 2015-10-06 16:57

Section 1

Question Answer
Sympathetic innervation to heartB1= BEAT
Sympathetic innervation to blood vesselsA1= constrict. B2= relax (except no B2 veins and genital)
GIT Secretions with sympathetic innervationDecrease (running away, don't need to digest)
A1 main fcnCONSTRICTION = Blood vessels, spincters, Pupilmm=mydriasis, Bladder sphincter, Splenic, Uterus, piloerector mm, ejaculation,
B1 Main fcnBeat = Up all heart, Renin, Relaxion sm mm of bladder and intestine, Lipolysis,
B2 Main fcnRelax smooth mm (eg blood vessels (not veins), bronchiole relax, Uterus relax, Spleen relax, Liver glucogenolysis/gluconeogenesis, increase NE release
A2 main fcnBlood effects= platelet aggregation, increase kidney renin release
Sympathetic exceptionM= sweatgland B2 in horse!
Parasympathetic exceptional oneM3 relaxes arterioles but do not have natural innervation
M2 Main effectsHeart effects down
M3 Main effectsRelax blood vessels, Constrict bronchioles, increase secretions
Muscarine toxicitySLUDGEM- Salivation, Lacrimation, Urination, Defecation, Gastrointestinal Distress, Emisis, Miosis
Genital parasympathetic vs sympatheticParasympathetic = Point = erection, Sympathetic =Shoot= ejaculation
Parasympathetic generallyRest and digest
Sympathetic generallyFight and flight
Sympathetic Nn exceptionAdrenal Medulla
memorize

Section 2

Question Answer
Alpha 1 G-coupledGq
Alpha 2 G-coupledGi- think inhibitory
B G-coupledGs think G-stimulatory
memorize

Section 3

Question Answer
3 components for antithrombotic drugsVascular wall, coagulation, platelets
Cumerin derrivitivesdicumorol (moldy sweet clover), warfarin (rat poison)
Antiplatelet drugsAspirin (Cox 1 inhibitor), Clopidogrel
Vasodilators (vascuclar wall) Acepromazine, hydrazine
Vascular wall antithroboticsanti-inflammatory drugs and vasodilators
AnticoagulantsCalcium chelators, heparin, Xa, IIa inhibitors, Vit K antags
ThrombolyticsStreptokinase, tissue-type plasminogen activator
Calcium ChelatorsSodium citrate, sodium oxalate, EDTA, Sodium fluoride (for blood collection)
Asprin inhibits?Thromboxane
ClopidogrelAntiplatelet
Erythropoietin (EPO)Increases RBC
rhG-CSFIncreases WBC
memorize