what should be looked for when prescribing SSRIs to children
Warning = antidepressants may increase the risk of suicidal thinking and behavior in some children and adolescents with Major Depressive Disorder (MDD).
how long should kids be monitored and which SSRI should be used
Monitoring = children and adolescents taking SSRI medications should be closely monitored for any worsening in depression, emergence of suicidal thinking or behavior, or unusual changes in behavior, such as sleeplessness, agitation, or withdrawal from normal social situations. Close monitoring is especially important during the first four weeks of treatment. = prozac
List one pro and one con each for the N-methyl-D-aspartate receptor (NMDA)
NMDA receptor hypothesis o Pros = glutamate is very important in brain (potential is great), many antidepressant treatments affect NMDA receptors long-term, preclinical data is positive o Cons = almost no clinical evidence that NMDA antagonists are effective antidepressants
List one pro and one con each for corticotropin-releasing factor (CRF) theories.
CRF hypothesis o Pros = CMST long has been a test of depression, CRF associated with control of GI system, CRF antagonists associated with reduced sleep, small clinical trial o Cons = no extensive clinical trials
Give the condition that anti-depressants are often used for but for which bupropion should not be used
Bupropion should not be used for panic or OCD as it may worsen panic and OCD (remember it seems to act on dopamine systems).
a chronic disturbance of mood involving depressed mood for most of the day more days than not, for at least two years.
Dysthymia (or Depressive Neurosis)
poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self-esteem, poor concentration or difficulty making decisions, and feelings of hopelessness.