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Pharm 3

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lunalovegood's version from 2016-10-04 01:41

Section

Schedule
Question Answer
Heroin, marijuana, LSD1
Amphetamines, codeine, meperidine, methadone, morphine, oxycodone2
Cocaine2
Codeines + aspirin or APAP3
Chloral hydrate4
Diazepam4
Phenobarbital4
Cough Rx with codeine5
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Equal
Question Answer
HydrocodoneVicodin (Hydrocodone is for Dr. House)
OxycodonePercocet (OxyContin) (more potent than hydrocodone)
DronabinolMJ synthetic
NabiloneMJ synthetic
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Stuff
Question Answer
Reward pathway - neurons of ___ contain _____ (NT) that is released in the _________ _________ and the prefrontal cortex.VTA, dopamine, nucleus accumbens.
Rapid form of tolerancetachyphylaxis
Withdrawal symptoms are autonomic hyperactivityopioids (dilated pupils, sweaty, hot, weakness, weight loss, restless)
Heroin enters CNS ______. Methadone _____.quickly, slowly (IV & lipid vs. oral)
Naloxoneopioid OD antidote
Clonidinehelps with high autonomic activity in opioid OD / withdrawal
Barbiturates - euphoria with _________ doseslow
BDZ - high affinity for ___ receptor - greater potential for abuseBDZ2
Withdrawal symptoms - worse for barbiturates or opioids?barbiturates (bar-bitch-ruates)
Xerostomia, pain in jaws & teethwithdrawal of BDZ
NaHCO3 (base)to remove toxic barbiturates
NH4Cl (acid)to remove toxic amphetamines
FlumazenideBDZ antagonist (toxic lvls)
CNS stimulants increase synaptic NT... NE & dopamine
Mydriasisdilation of pupil (stimulants)
Depression, dysphoria, tremor, fatigue, pain, nightmare, sleep disturbanceswithdrawal of Cocaine
LSD activates ___ receptorsserotonin
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