robbypowell's version from 2015-11-06 03:57


Question Answer
4 types of cells in epidermisKeratinocytes, melanocytes, Langerhan’s cells & merkel cells
What layer of skin is skin found in Fibrous tissue, adnexal structures, vessels, nervesDermis
3 Adnexal structures in skinSebaceous glands, Hair, Sweat glands
T/F: Squamos epithelium of the skin is made up of only squamos cellsFalse (many other types can be there as well... such as melanocytes)
Bacterial infection of the skin from Staph aureus or Strep pyogenesImpetigo
Bacterial infection of the skin from PseudomonasAbscess
Two viral infections that can affect the skinHPV (Human Papilloma Viruses) & HSV (Herpes Simplex Virus)
____ & ____ cause Superficial fungal skin infectionsTinea & Candida
____ & ____ cause DEEP fungal skin infectionsHistoplasma & Aspergillous
papilloma, verruca vulgaris, verruca plana, condyloma are all examples of ____ caused by ____Warts; HPV
Urticaria, Eczematous dermatoses, & Erythema multiforme are 3 examples of _____ dermatosesACUTE Dermatoses
____ & _____ are blistering non-infectious disordersPemphigus & Pemphigoid
3 examples of Chronic DermatosesPsoriasis, Lichen Planus, & Lichen Simplex Chronicus
Is Pemphigus infectious/contagious?no
2 Neoplastic conditions of Surface EpitheliumSCC & BCC
What is a malignant neoplasm of melanocytes?Melanoma
What is a benign neoplasm of melanocytes?Melanocytic Nevi
Papilloma,Verruca, & Condyloma are examples of ____ (benign/malignant) neoplasms of surface epitheliumBENIGN
____ begins as a single small erythematous macule, spreading and acquiring a golden crust. It is spread through direct contact.Impetigo
Underneath the microscope, Impetigo presents with the accumulation of ___ and ____ beneath the stratum corneumCocci (bacteria) & Neutrophils
Warts tend to be much worse in what type of patients?Immunocompromised
Define: Epithelial cells affected by HPVKoilocytes
The mitotic rate of cells w/ HPV is _____ than normal epithelial cellsHigher
Chicken Pox and Shingles are caused by what?Herpes Zoster
Inflammatory skin conditions that are not related to infectionsDermatoses
What type of infection is Impetigo?Bacterial
Two main bacteria that cause ImpetigoS. Aureus & Strep Pyogenes
Vaccines are recommended for patients over 50 yo for what condition?Herpes Zoster (Varicella Zoster) (shingles)
What is the treatment for Impetigo?Topical Antibiotic
Viral skin infection that causes neoplasiaHPV
Destructive viral skin infectionHerpes Simplex Virus
Most of the time, Herpes infections we see in adults are ____ and the ____ infection was in childhoodSecondary; Primary
Vesicles on a skin dermatome with neuropathic pain ... caused by what?Herpes Zoster
common disorder mediated by localized mast cell degranulation, which leads to dermal microvascular hyper permeabilityUrticaria
name of erythematous, edematous, and pruritic papules from UrticariaWheals
What causes Urticaria?Mast cell degranulation in dermal tissue (except for one exception)
What cells are responsible for Hives? (normally)Mast cells (degranulation)
What Immunoglobulin coats Mast cells?IgE
Urticaria is caused by ____ ____ degranulation except in the one case of _____ ______ where it is caused by activation of the complement systemMast Cell; Hereditary Angioedema
Urticaria from hereditary angioedema is caused by what?Activation of Complement System
Hives present as ____ with itchy and/or burning sensationWheals
Allergic contact dermatitis response to nickel jewelry is an example of ____ ____ ____Acute Eczematous Dermatitis (allergic Contact dermatitis)
Dilated and tortuous blood vessels within the papillae, bleed readily when the scale is removed, giving rise to multiple punctate bleeding points is known as the _____ signAuspitz sign
multifactorial (genetic and environmental) immunologic disease; associated with Koebner phenomenonPsoriasis
_____ phenomenon: damage to skin can induce autoimmune lesionsKoebner phenomenon
allergic response that results in well-demarcated, pink to salmon–colored plaque covered by loosely adherent silver-white scalePsoriasis
lysis of the intercellular adhesive junctions between neighboring squamous epithelial cells that results in the rounding up of detached cellsAcantholysis
The common feature of all forms of PemphigusAcantholysis
In _____ _____, acantholysis selectively involves the layer of cells immediately above the basal cell layer, giving rise to a suprabasal acantholytic blisterPemphigus Vulgaris
Cellular Infiltrate in Pemphigus?Lymphocytes, Macrophages, Eosinophils
Blistering in ____ ____ is triggered by the linear deposition of IgG antibodies and complement in the epidermal basement membraneBullous Pemphigoid
2 Treatments for Bullous PemphigoidCorticosteroids & Immunosuppressants
Which Chronic Autoimmune Dermatosis results in loss of dermo-epidermal adhesion because IgG antibodies to Collagen type 17?Bullous Pemphigoid
In Bullous Pemphigoid.... the antigen, ______, is recognized by the ______ antibody (immunoglobulin)Collagen type 17; IgG
IgE-______ Urticaria is associated with reactions to Pollen, food, venom, drugsIgE Dependent
IgE-______ Urticaria is associated with reactions to Opiates & antibioticsIndependent
IgG bound to the surface of Keratinocytes is diagnostic for what condition?Pemphigus Vulgaris
Pemphigus Vulgaris affects: (A) Skin, (B) Mucosa, (C) Skin & MucosaSkin & Mucosa
Most common form of PemphigusPemphigus Vulgaris
Pemphigus Vulgaris is an ______ disease... this in response to a protein expressed in _____Autoimmune; Desmosomes
Autoimmune condition causing Suprabasal acantholysisPemphigus Vulgaris
Pemphigus Vulgaris and Bullous Pemphigoid both have autoimmune causes involving which type antibody?IgG
Bullous Pemphigoid is an autoimmune response to collagen in the _____ _____Basement membrane

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