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Path- muscles (emergency fast)

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kelseyfmeyer's version from 2015-09-08 17:03

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Question Answer
which band doesnt moveA band doesnt move, I MOVE!
mm hyperplasia--> due to what, is it inc in size or # of mmmutation of MYOSTATIN GENE. inc NUMBER OF MYOFIBERS (so...i want to PLAY with MORE people) (double mming happens in calves)
MYOFIBRILLAR HYPOPLASIA--> dec number or size?NUMBER. ( i want to PLAY with LESS people)
HYPERKALEMIC PERIODIC PARALYSIS (HYPP)--> what causes this?SKELETAL MUSCLE NA CHANNEL GENEdefect, causes hyperkalema
ARTHROGRYPOSIS--> what is happening to the mm fibers and why?DEC IN SIZE bc of lack of innervation (makes sense, just atrophy but its all there)
is atrophy dec size or numberdec size
Senile Atrophy charateristiclipofucinin
hypertrophy--> inc number or size?size
STEATOSIS (lipomatosis)--> what causes this and what happensDEFECTIVE MYOFIBER DEVELOPMENT --> REPLACED WITH FAT
how would you describle mm distrophy? how does this happen?progressive and degenerative (abnormal proteins). There is an X-linked genetic type in dogs“Duchenne muscular dystrophy”, and also HMLR (Hereditary Myopathy of Labrador Retrievers)
color of severe calcification?chalky white
color of mm when there's degenerationpallor
4 common mechanisms of necrosishypoxia (atp depletion), free radicals, membrane damage, Ca influx--> mito damage
what cells heal mm?satellite cells
white mm dz is caused by?selenium and vit E deficiencies
why does lack of vit e/Se cause white mm dz?these two things responsible for peroxidation, which prevevnts free radical damage
what kinda necrosis does white mm dz cause? what are the three lesions?(segmental necrosis) HYPEREOSINOPHILIA, LOSS OF STRIATIONS, CALCIFICATION
exertional rhabdomyolysis--> what happens and what are the clinical signs?Forced exercise after rest during which feed was not restricted--> renal failure and myoglobinuria-->MYOGLOBINURIC NEPHROSIS =dark black kidneys
what is happening in capture myopathy and what are the leisons like?freaking out--> lactic acid--> acidosis--> bilaterally symmetrical lesions of PALE, SWOLLEN, EDEMATOUS MUSCLES
what is an example of an ionophore, what does it do to mmmonensin -- >ILL DEFINED PALE STREAKS IN SKELETAL AND/OR CARDIAC MUSCLE
what does HYPOkalemia do?hypo--> hyperpolarzied--> weakness
two clinical signs of hypophosphatemia?neuro and hemolytic signs
PORCINE STRESS SYNDROME (PSS)--> what kinda problem is this? what happenes?HYPERMETABOLIC SYNDROME--> DEFECT IN UPTAKE, STORAGE, AND RELEASE OF CA2+ (pigs eat tums when theyre stressed out)
DEEP PECTORAL MYOPATHY-->whats happening?vigorous flapping of wings causes damage from vascular compression
which two endocrine dzs affect mm, and how?HYPOTHYROID and HYPERCORTISOL. DENERVATION!!! ATROPHY
black leg caused by? what happens and what's the exudate?Clostridium chovi, there is INGESTION OF SPORES, then injury triggers endotoxin release. there is SEROHEMORRHAGIC EXUDATE
EOSINOPHILIC MYOSITIS happens in who, why?rumis. eosinophil=parasite=HYPERSENSITIVITY TO SARCOCYSTIS INFECTION **NOTE: GREEN=EOSINOPHIL. IDIOPATHIC!!!
MASTICATORY MUSCLE MYOSITIS--> who? why?dogs. IMMUNOLOGIC -->AB TO TYPE IIC MYOFIBERS. see SWOLLEN FIBERS WITH INFILTRATION OF EOSINOPHILS
POLYMYOSITIS--> what is this in who?This is a LYMPHOPLASMACYTIC inflammation (IMMUNE!!!)
PURPURA HEMORRHAGICA--> who, whats happeninghorses, autoimmune complexes after strangles
wooden tongue caused by with what CS?actinobacillus lignersii with sulfur granules
lumpy jaw caused by with what CS?actinoMYCOSIS, granuloomas with CASEOUS-suppurative centers
TRICHINOSIS VERSUS CYSTICERSOSI--> how does this affect musclesTRICH: ENTERS CELL. CYST: RESIDE IN MM
RHABDOMYOMA looks like?Large PEDUNCULATED mass
RHABDOMYOSARCOMA looks like?RHABDOMYOSARCOMA, SPHERICAL
BOTRYOID RHABDOMYOSARCOMA looks like?grapes
Congenital MYASTHENIA GRAVIS bc?LOW # OF Ach RECEPTORS
acquired myaesthenia gravis bc?AUTOiMMUNE To ach receptors
BOTULISM--> how does this affect mmClostridium botulinum --> TOXINS --> PREVENT Ach RELEASE
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