cats. MOST COMMON CAUSE OF TUMORS IN CATS!!! (THERE IS ALSO A KNOWN ETIOLOGY- FELINE SARCOMA VIRUS)
what is more common, a fibroma or a fibrosarcoma?
fibrosarcoma--> (sadface. remember that there is a feline sarcoma virus and you'll remember which is more common)
where do fibrosarcomas usually occur on cats? what are the three possible causes?
important bc KNOWN etiology! usually occur on trunk/extremities. (1) Virus induced--> feline sarcoma virus!!! FeLV also contributes--> Oral cavity (2) Non-virus induced- inflammation trauma--> older cats (3) Vaccine assoc- from adjuvant- very aggressive
what do you want to know about vaccine-associated fibrosarcoma in cats? (cause, preventative measures?)
from ADJUVANT in vx. Vx at DISTAL TIBIA for easy amputation
what does the histology of a fibrosarcoma look like?
where do fibrosarcomas usually occur in dogs? (three places and possible etiologies)
(1) usually on trunk and extremities. can be in association with the parasite SPIROCERCA LUPI (I tried to eat a spirocerca lupi, but it was very fibrous). (2) oral cavity- periosteum of maxilla and mandible. (3) bone
from histiocytes (macrophages)( Langerhans cells) in SKIN
what is unusual about a histiocytoma?
fast growing but benign
who are histiocytomas common in?
DOGS (all the pictures were dogs. also That Dawg sure liked Histo!)
what is the gross appearance of a histiocytoma?
solitary, dome shaped, bright red, grow rapidly,”BUTTON” tumor bc depressed in center from necrosis (histio pushed his buttons--- NOT THE WED WON)
what is the microscopic appearance of a histiocytoma?
(macrophages) round to polygonal cells, arranged in cords or solid sheets (histo is a class that had many shaped cells, round or polygonal, and you could learn with cords, aka comps, or sheets, aka paper)
where do MCTs occur in DOGS? size? clinical signs? histo?
SKIN most common site, can be small to large. Clinical signs caused by histamine: pruritus, nausea, vomiting, diarrhea, anemia, GI ulcers. Histo: mast cells and eosinophils USUALLY present
where to MCTs occur in CATS? (2) clinical signs for each?
(1) cutaneous- Clinical signs: edema of limbs, pruritic papillocrustus all over body, lymphadenopathy(huge LNs) (2) visceral-->SPLEEN (most common abnormality of feline spleen). Clinical signs: small ulcers in stomach and duodenum- hyperhistaminemia (MASTS JABBING THROUGH A CATS SKIN AND INTO ITS SPLEEN)
how can you tell a MCT from another round cell tumor?
Their blue purple granules stained with Wright or Giemsa stain, OR if poorly granulated, special stain toluene blue
Lymphosarcoma/ Lymphoma= MOST common neoplasm in animals!!!!!!!!!!!!!!!!!!!!!!!
what are the different types of lymphosarcomas/lymphomas CATS get? what is the etiology?
etiology= FeLV and FIV--> hemopoietic tumors(90% of hemopoietic tumors in cats are lymphosarcomas). MOST COMMON type is alimentary, there is also a mediastinal (NOT hypercalcemia, unlike dog), multicentric, and extranodal form. (If you're a cat, a LN full of retroviruses is yummy!)
what are the different types of lymphosarcomas/lymphomas DOGS get? what is the etiology?
etiology= NO VIRAL ETIOLOGY. MOST COMMON type is MULTICENTRIC(mult LNs)--> *HYPERCALCEMIA*. there is also alimentary, mediastinal*HYPERCALCEMIA., cutaneous, extranodal (dogs love calcium so much they put it in their MULTIPLE LNs apparently, also sometimes their heart <3 because they love it)
what are the different types of lymphosarcomas/lymphomas CALVES/CATTLE(differentiate the age on these) get? what is the etiology?
types= CALF (young), THYMIC (young), SKIN(young), (<--these 3 not contagious, deemed "sporadic") and Enzootic leukosis--> BLV. mature cattle- can occur anywhere in body (cattle LNs are scrutinized all the time, and age matters! 3 baby LNs and then a virus if you're an old cattle)
which cells are affected in a hemangiosarcoma? is it benign or malignant?
endothelial cells lining bvs, highly malignant
how common is hemangiosarcoma in dogs? where does it usually occur? what are the clinical signs?
common in dogs, usually in the SPLEEN! clinical signs are sudden collapse bc rupture of tumor (lots of blood vessels in the dog spleen...lots of chances to die. also note that hemangiosarcoma in dog spleen, but in cat spleen it's MCTs)
how common is hemangiosarcoma in cats? where does it usually occur?
less common, in skin (cats won this round over dogs-- a bunch of BVs in your skin is no big deal.)
what happens if there is a hemangiosarcoma in the bone?
it is VERY destructive, which is why one of the clinical signs can be LAMENESS (blood exploding out of the bone and shattering it)