Path 1- Integumentary Glossary Terms

kelseyfmeyer's version from 2015-04-16 19:01

Da terms, yo

Question Answer
Acantholysisloss of cohesion between keratinocytes caused by the breakdown of intercellular bridges.
Acanthosisthickening of the spinous cell layer (stratum spinosum) of the epidermis. (a SPINEY can)
Acraldistal parts of the extremities.
Alopeciahair loss.
Anagenphase of hair cycle in which hair synthesis takes place.
Anaplasialack of cellular differentiation and organization, a feature of neoplastic cells.
Angioedemavascular reaction involving the deep dermis or subcutis and consisting of edema manifested as giant wheals and caused by dilation and increased permeability of capillaries (deeper version of urticaria).
Apoptosisprogrammed cell death.
Atrophyreduction in size of a cell, tissue, organ, or part.
Ballooning degenerationmarked intracellular fluid accumulation IN the cells of the epidermis.
Blister (vesicle or bulla)localized collection of fluid usually in or beneath the epidermis.
Bullalarge blister (≥1.0 cm).
Carcinoma in situa malignant neoplasm of epithelial origin that has not invaded through the basement membrane.
Catagentransition phase of the hair cycle between growth and resting phases.
Cellulitisan acute bacterial infection of the dermis and subcutis that spreads to surrounding soft tissues and is characterized by erythema, warmth, swelling, and pain. The source of the infection is most often a penetrating wound in the area of infection. Cellulitis can also cause fever and enlarged lymph nodes.
Comedo (pl., comedones)plug of follicular stratum corneum and dried sebum in a hair follicle that leads to follicular distention.
Cornificationproduction of stratum corneum by terminal epidermal differentiation.
Crustmaterial formed by drying of exudate or secretion on the skin surface.
Cytokinessmall molecular weight protein molecules (generally <30 kD) that are mediators of inflammation and growth
Dematiaceousnaturally pigmented black or brown mycelium(mass of hyphae) or conidium(broom-looking fungus thing)....(so, dark stuff growing bc of fungus)
Dermatitisinflammation of the skin.
Dermatophytosisinfection of the stratum corneum of the epidermis, hair, or claws with fungi of the genera Microsporum, Epidermophyton, or Trichophyton.
Dermatosisnoninflammatory lesion of the skin.
Dyskeratosisabnormal, premature, or imperfect keratinization.
Dysplasiaabnormal development; term may be used in association with a congenital or inherited developmental anomaly or in association with an abnormality in maturation of cells within a tissue.
Effluviumshedding of hair.
Elastosisdegeneration of dermal connective tissue leading to accumulation of elastotic fibers; sometimes seen with solar dermatitis.
Epidermal collaretteperipheral expanding ring of scale.
Epidermitisinflammation of the epidermis.
Epidermolysisseparation of the epidermis from the dermis.
Epidermotropic/Epitheliotropichaving a predilection to enter the epidermis or other epithelial structures as seen with cutaneous T cell lymphoma (mycosis fungoides).
Erosionloss of the superficial layers of the epidermis.
Eruptionrapid development of skin lesion associated with redness.
Erythemaredness of skin caused by congestion of capillaries.
Excoriationsuperficial loss of epidermal layers caused by physical trauma (scratching).
Exfoliationshedding of layers or scales.
Exogenthe stage of the hair cycle where old hairs are shed.
Exudatefluid, cells, or debris from blood vessels deposited in or on other tissues.
Fissurecleft or groove.
Folliculitisinflammation of a hair follicle.
Furunclecircumscribed, painful nodule (accumulation of pus) in the dermis secondary to follicular rupture.
Furunculosisrupture of follicles usually caused by inflammation, distention, and/or trauma leading to entry of follicular contents into the dermis.
Genodermatosisa genetically determined disorder of the skin.
Glabroussmooth skin, hairless skin.
Hamartomaa localized, tumorlike malformation of mature cells and tissues that includes normal components of the organ in which the hamartoma arises but that is disorganized, present in excess, and sometimes larger than normal. Usually, one tissue element predominates (e.g., follicular hamartoma, vascular hamartoma). A hamartoma is not a true neoplasm because it involves the proliferation of more than one cell type and often includes the development of complex structures such as arteries or follicles.
Hydropic degenerationintracellular fluid accumulation in cells of the basal epidermis.
Hyperkeratosishistologic term for thickening of stratum corneum.
Hyperplasiaincrease in the number of normal cells.
Hypoplasiaincomplete development.
Hypotrichosisless hair than normal.
Ichthyosiscongenital skin disorder in which the skin is thickened by scales (hyperkeratosis) that can crack into plates resembling fish scales.
Impetigobacterial dermatitis characterized by pustules.
Indolentslow growing, a term applied to persistent ulcers on the lips of cats, and sometimes incorrectly called “rodent ulcer,” a term from the human literature used to refer to ulcerated basal cell carcinoma.
InduratedHardening of the skin as a result of inflammation or fibrosis. (DURable)
Interfaceinflammation arranged in a layer close to and often obscuring the epidermaldermal junction (interface), and with vacuolated (hydropic degeneration) and sometimes apoptotic basal cells; the inflammation can be mild (cell poor) or extensive (cell rich).
Intertrigodermatitis that develops because of friction between apposing skin surfaces (e.g., adjacent folds).
Keratinocytesthe epidermal cells that synthesize keratin and comprise more than 90% of epidermal cells.
Keratosis (pl., keratoses)an uncommon to rare circumscribed papular, plaquelike, or linear focus of proliferative keratinocytes covered by thick stratum corneum; keratoses can be caused by sun exposure (solar or actinic keratoses) or can be idiopathic (lichenoid, linear, cannon [metatarsal bone] keratoses).
Kerionan intense focal folliculitis usually caused by a dermatophyte infection. (KERI's hair looked like shit because her follicles were inflamed by fungi)
Langerhans’ cellsintraepidermal dendritic antigen-presenting cells.
Lichenificationthickening of skin with accentuation of skin creases caused by marked acanthosis.
Lichenoidconfusing term that generally refers to a dense zone of dermal inflammation parallel to the epidermis usually without basal cell injury.
Lichenoid dermatosis (es)the conventional term for uncommon to rare, often idiopathic, single or grouped papules, plaques, or papillomatous foci covered by scale, and histologically composed of epidermal hyperplasia, lichenoid lymphoplasmacytic dermal inflammation, hyperkeratosis, and parakeratosis. The term dermatitis is probably better than dermatosis as inflammation is present in these lesions.
Maculeflat, circumscribed lesion of altered skin color.
Melaninthe dark granular pigment produced by melanocytes that is responsible for the brown coloration of hair, skin, and other tissues such as the iris and choroid of the eye.
Melanophagemacrophage containing ingested melanin.
Merkel cella neuroendocrine cell found in the stratum basale.
Mucinglycosaminoglycan (GAG), a normal component of the intercellular ground substance of the dermis, consists of protein bound to hyaluronic acid.
Myceliuma mass of hyphae.
Mycetomaa slowly progressive infection of the cutaneous and subcutaneous tissue, fascia, and sometimes underlying bone caused by traumatic implantation of actinomycetes (actinomycotic mycetoma) or fungi (eumycotic mycetoma).
Myxedemanonpitting edema of the skin because of abnormal deposits of mucin in the dermis.
Necrotizing fasciitisan acute serious lifethreatening subtype of cellulitis usually caused by streptococcal bacterial infection and toxin production, and located within the subcutaneous fat and fascial planes. The clinical lesions are painful, hot, and swollen areas with extensive exudation and necrosis. The condition can progress rapidly and result in systemic shock.
Nevuscircumscribed malformation of the skin assumed to be of congenital or inherited origin, and consisting of any component of the skin. The term “hamartoma” is preferred to nevus to avoid confusion with the pigmented nevus (mole) that arises in the skin of humans.
Nodulea circumscribed, solid elevation of skin (≥1 cm).
Onychodystrophyabnormal formation of the claw.
Onychomadesissloughing of claws.
Panniculitisinflammation of subcutaneous adipose tissue.
Papulecircumscribed, solid elevation of skin (<1 cm).
Parakeratosisretention of pyknotic(chromatin condensed) nuclei in epidermal cells of the stratum corneum.
Paronychiainflammation of skin around the claws. (PARes stuck around the claws)
Pautrier’s microabscessa localized intraepidermal collection of neoplastic lymphocytes characteristic of epitheliotropic lymphoma (mycosis fungoides).
Pemphigusa group of cutaneous diseases associated with blistering.
Phaeohyphomycosismycotic disease caused by pigmented fungi (dematiaceous fungi) of a variety of genera and species that do not form sclerotic bodies or granules.
Pigmentary incontinencemelanin pigment within dermal macrophages or free in the dermis developing via injury to pigment containing basal layer cells.
Plaquea flattopped, solid elevation in the skin that occupies a relatively large surface area in comparison with its height (≥1 cm).
Pustulesmall, circumscribed accumulation of pus within the epidermis or within a hair follicle.
Pyodermapyogenic (pusproducing) bacterial infection of the skin.
Rodent ulcera term used in human medicine to define an ulcerative basal cell carcinoma; sometimes used inappropriately in veterinary medicine to refer to an indolent ulcer affecting the lip of cats.
Scalea thin, platelike accumulation of stratum corneum on the surface of skin.
Seborrheanonspecific term for clinical signs of scaling, crusting, and greasiness. Primary seborrhea is a more specific term applied to inherited cornification disorders.
Sebumsecretion of sebaceous glands.
Spongiosisintercellular edema, which, by widening of the intercellular space and stretching of the “intercellular bridges,” creates a spongelike appearance to the epidermis.
Telogenresting phase of the hair cycle.
Ulcerfull thickness loss of the epidermis with extension into the dermis
Urticariausually transient vascular reaction in the upper dermis consisting of edema manifested clinically as wheals (hives); a more superficial version of angioedema.
Vesiclesmall blister within the epidermis or at or below the dermalepiderma interface (<1.0 cm)
Vibrissa (pl., vibrissae)long, coarse hair located about the nose (sinus hair, tactile hair).
Vitiligoacquired disorder characterized by circumscribed areas of depigmentation in the skin.
Whealsmooth, circumscribed, slightly elevated area on skin caused by dermal edema.
Yeastunicellular budding fungus.

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