Create
Learn
Share

Patch Clamp Configurations

rename
imissyou419's version from 2016-10-16 02:20

Section

Question Answer
cell-attachedcan do V-clamp only, able to record single channels (not good for membrane potential), inside of cell still native
whole cellcan do I-clamp & V-clamp, measure membrane potential, not good for recording single channels, study ligand working from extracellular side, replace intracellular solution with pipette solution
inside-outcan do V-clamp only, able to record single channels, study ligand working from intracellular side
outside-outcan do V-clamp only, able to record single channels, study ligand working from extracellular side, replace intracellular solution with pipette solution
single channel current is constant (at a fixed voltage), instantaneous, random
memorize

Recent badges