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Parasympathetic drugs

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lilyo's version from 2016-06-10 19:45

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Question Answer
Bethanecholdirect agonist, bowel and bladder motility (post-op ileus, neurogenic ileus, urinary retention)
Carbacholdirect agonist, constricts pupil and relieves intraocular pressure in open-angle glaucoma
Methacholinedirect agonist, asthma diagnosis
Pilocarpinedirect agonist, potent stimulator of sweat, tears, saliva; open-angle and closed-angle glaucoma, xerostomia (Sjogren syndrome)
Donepezil, galantamine, rivastigmineanticholinesterase, alzheimer disease
Edrophoniumanticholinesterase, diagnosis of myasthenia gravis (now myasthenia gravis is diagnosed by anti-acetylcholine receptor antibody test)
Neostigmineanticholinesterase, post-op and neurogenic ileus and urinary retention, reversal of NMJ blockade post-op
Physostigmineanticholinesterase, anticholinergic toxicity; crosses BBB CNS
Pyridostigmineanticholinesterase, myasthenia gravis (long-acting), does not penetrate CNS
Atropine, homatropine, tropicamidemuscarinic antagonists, mydriasis and cycloplegia
Benztropinemuscarinic antagonist, Parkinson disease and acute dystonia
Glycopyrrolatemuscarinic antagonist, preop use to reduce airway secretions
Hyoscyamine, dicyclominemuscarinic antagonist, antispasmodics for IBS
Ipratropium, tiotropiummuscarinic antagonist, COPD and asthma
Oxybutynin, solifenacin, tolterodinemuscarinic antagonist, reduce bladder spasms and urge urinary incontinence
Scopolaminemuscarinic antagonist, motion sickness
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