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Paraneoplastic syndromes

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osborn's version from 2017-11-07 18:58

endocrinopathies

Question Answer Column 3
Cushing syndromeSmall cell carcinoma of lung,Pancreatic carcinoma,Neural tumorsACTH or ACTH-like substance
Syndrome of inappropriate antidiuretic hormone secretionSmall cell carcinoma of lung; intracranial neoplasmsAntidiuretic hormone or atrial natriuretic hormones
HypercalcemiaSquamous cell carcinoma of lungBreast carcinoma,Renal carcinoma,Adult T cell leukemia/lymphoma,Ovarian carcinomaParathyroid hormone–related protein, TGF-α, TNF, IL-1
HypoglycemiaFibrosarcoma,Other mesenchymal sarcomas,Hepatocellular carcinomaInsulin or insulin-like substance
Carcinoid syndromeBronchial adenoma (carcinoid),Pancreatic carcinoma,Gastric carcinomaSerotonin, bradykinin
PolycythemiaRenal carcinoma,Cerebellar hemangioma,Hepatocellular carcinomaErythropoietin
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nerve and muscle syndrome

Question Answer Column 3
MyastheniaBronchogenic carcinoma, thymomaImmunologic
Disorders of the central and peripheral nervous systemsBreast carcinoma, teratoma
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dermatologic disorders

Question Answer Column 3
Acanthosis nigricansGastric carcinoma,Uterine carcinoma,Lung carcinomaImmunologic; secretion of epidermal growth factor
DermatomyositisBronchogenic and breast carcinomaImmunologic
Hypertrophic osteoarthropathy and clubbing of the fingersBronchogenic carcinomaUnknown
Venous thrombosis(Trousseau phenomenon)Pancreatic carcinoma,Bronchogenic carcinoma,Other cancersTumor products (mucins that activate clotting)
Nonbacterial thrombotic endocarditisAdvanced cancersHypercoagulability
AnemiaThymomaImmunologic
Nephrotic syndromeVarious cancersTumor antigens, immune complexes
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