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PAH & PF

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munsele's version from 2016-07-06 15:25

Section

Question Answer
RevatioViagra
EpoprostenolTachycardia, hypotension, flushing, jaw pain, and N/V/D
Riocigautadempas
Adempas admin/dosingdose needs to be increased in smokers, do not give in PG
TracleerBosentan
Veletriheat stabilized version of epoprostenol
Veletri dosinglarge sudden reductions in dose should be avoided
Non Cat X PAH medsTadalafil and epoprostenol
Potential causes of PAHillegal drug use, certain chemo medications (dasatinib)
Non pharm tx options for PAH ptsSodium restriction, avoiding high altitudes, maintaining a constant fluid volume status
Pulmonary vasodilator mechIncrease cAMP, increase cGMP, antagonize endothelin receptors
Flolarf adminrequires cooling packs, back up pump, must keep catheter clean
PAH meds requiring REMSendothelin antagonists
Nintedanib MOAtyrasine kinase inhibitor
PF medsNintedanib and pirfenidone
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