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P450 enzyme system

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sxkerr's version from 2016-04-24 13:19

Section

Question Answer
antiepileptics: phenytoin, carbamazepineInducers
barbiturates: phenobarbitoneInducers
rifampicinInducers
St John's WortInducers
chronic alcohol intakeInducers
griseofulvinInducers
smoking (affects CYP1A2, reason why smokers require more aminophylline)Inducers
memorize

 

Question Answer
antibiotics: ciprofloxacin, erythromycinInhibitors
isoniazidInhibitors
cimetidine, omeprazoleInhibitors
amiodaroneInhibitors
allopurinolInhibitors
imidazoles: ketoconazole, fluconazoleInhibitors
SSRIs: fluoxetine, sertralineInhibitors
ritonavirInhibitors
sodium valproateInhibitors
acute alcohol intakeInhibitors
quinupristinInhibitors
memorize