Ovarian Cancer - Other Tumors

omarys's version from 2017-05-10 22:04

Section 1

Question Answer
All of the facts in this section relate toGerm cell tumors
Make up _________% of ovarian tumors25
Mostly benign _____teratomas
These tumors grow ______ (rate?) and are therefore usually ________ (symptoms?)rapidly ; symptomatic
Germ cell tumors affect women _____ than 20 years oldyounger
Staging the tumors is surgical, just like in ______ ovarian tumorsepithelial
5-year survival is _____ (high/low)High, >95%.
There are ______ (no/several) markers associated with this tumor.Several: hCG, aFP, CA-125, and LDH. The first two are probably the most important?
The initial tx is:surgical removal
Tx may also include:chemotherapy (BEP x 3 rounds)
Both mature and immature teratomas are _____ (+ or -) for both hCG and alpha feto protein.Negative. Teratomas arise from germ cells that undergo EMBRYONIC differentiation.
From the primordial germ cells, either embryonal carcinoma or __________ may arise as cancers.Germinoma / dysgerminoma
The embryonal carcinoma "branch" may undergo embryonic differentiation or _______ differentiation.Extraembryonic
The yolk sac and trophoblast arise from the ______ differentiation branch.Extraembryonic
A cancer that arises from trophoblasts, is hCG+ but aFP-.Choriocarcinoma
A cancer that arises from yolk sac cells, is aFP+ but hCG-.Endodermal sinus tumor

Section 2

Question Answer
All of the facts in this section relate toSpecialized gonadal-stromal tumors (=sex cord-gonadal stromal tumor)
The tumors have _____ (high/low) malignancy potential.low
Vast majority of tumors are __lateral and _____ (confined/diffuse)uni ; confined
The tumors can disturb the menstrual cycle, cause endometrial hyperplasia, and cause virilization because they _____ ________secrete hormones
Tx isSurgical removal (USO- unilateral salpingo-oophorectomy)
Chemotx is ______ (routine or common/not common)not common, given in less than 5% of cases

Section 3

Question Answer
All of the facts in this section relate tononspecific mesenchymal neoplasms
Malignant tumors include (1)Sarcoma
Benign tumors include (4)Lipoma, leiomyoma, fibroma, hemangioma
______ can either be primary (originating in ovaries) or occur elsewhere and metastasize to the ovariesLymphomas
Most of the tumors are _____ (benign/malignant)benign

Section 4

Question Answer
All of the facts in this section relate toMetastasis that causes (secondary) ovarian tumors
Metastases from the GIT are calledKrukenberg tumors
Other than the GIT, common cancers that metastasize to the ovaries are (3)Breast, endometrial, lymphoma