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Oncology Final

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munsele's version from 2016-05-02 22:24

Section 1

Question Answer
CrCl(140-age)x(wt in kg) / 72 x SrCr
BSAHt(cm) x Wt (kg) / 3600 -> square root of answer
ANCWBCx(%segs+%bands) / 100
Corrected CaCa2+ + [0.8x(4-albumin)]
Calvert EquationTarget AUC x (GFR + 25)
memorize

Section 2

Question Answer
CisplatinNephrotoxicity, and ototoxicity
CarboplatinNephro and ototoxicity
Doxorubicincardiotoxicity
Bleomycinpulmonary tox
Cyclophosphamidehemorrhagic cystitis
Vincristine and vinca alkaloidsperipheral neuropathy
Bevacizumabhypertension and bleeding
Cetuximabinfusion reactions prophylaxis required, acneiform rash
Panitumumabinfusion rxn, acneiform rash
Pertuzumabperipheral neuropathy, rash
TrastuzumabInfusion rxn; prophylaxis required
Ibrance (palbociclib)URI
Tarceva (erlotinib)acneiform rash
Crizotinibedema, disorder of vision
Platinum agents (alkylating agents)Sterility, infertility
Antimetabolites (pemetrexed, capecitabine, 5-FU, gemcitabine, MTX, cytarabine, 6-MP, Fludarabine)mucositis
Antimicrotubules (taxanes)Peripheral neuropathy
Nitrogen mustards (chlorambucil, cyclophos, mechlorethamine, procarbazine)Sterility, infertility
Irinotecanmucositis
ObinutuzumabHep B reactivation
RituximabInfusion rxn
Ibrutinib (Imbruvica)peripheral edema
Imatinib (Gleevec)Rash
Arsenic trioxideQT prolongation
Sorafenib (Nexavar), LapatinibRash, hand-foot syndrome
Opdivo (nivolumab)Hyperglycemia, musculoskeletal pain
Etoposidealopecia
NilotinibQT prolongation
RegorafenibHand-foot syndrome, HTN
All-trans retinoid acidretinoid acid syndrome (fever, resp distress, weight gain)
Ziv-afliberceptHTN, proteinuria
memorize

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