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Nursing Pharm Unit 4 Drugs

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olanjones's version from 2016-08-01 21:35

Endocrine

Question Answer
desmopressin/DDAVPAntidiuretic hormone - treatment of neurogenic DI (not effective against nephrogenic DI)
levothyroxine/LevothroidThyroid hormone - treatment of hypothyroidism
propylthiouracil/PTUAntithyroid agent - treatment for hyperthyroidism (sodium iodide-131 is also used for this condition)
hydrocortisone/CortefCorticosteroid - treatment of Addison's but also for non-endocrine conditions to suppress immune/inflammatory response (RA, IBD, Asthma, Edema, etc)
human regular insulin/Humulin RPancreatics/Antidiabetic hormone - short duration: slower acting (bolus) treatment of DM (most often type I) Onset = 30-60 mins, Peak = 1-5 hours
metformin/GlucophageHypogylcemic agent - Oral agent for decreasing hepatic production of glucose in treatment of DM II (not effective in type I)
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Reproductive

Question Answer
conjugated estrogen/Cenestin, PremarinEstrogen hormone - HRT, prevent conception, and treatment of neoplasms (inoperable breast cancer, prostate cancer)
medroxyprogesterone acetate/ProveraProgestin hormone - Dysfunctional uterine bleeding, prevent conception, and treatment of neoplasms
estradiol& norethindrone/Ortho-NovumMonophasic oral contraceptive - Prevent conception, regulate menstrual cycle, treatment of heavy menstrual bleeding
oxytocin/Pitocinstimulate L&D when indicated, control postpartum uterine bleeding
testosteroneTestosterone hormone - Delayed onset of puberty, hypogonadism, androgen responsive breast cancer
sildenafil/ViagraErectile dysfunction agent, vasodilator - Erectile dysfunction. CONTRAINDICATED in patients taking nitrates (CV collapse)
finasteride/ProscarAndrogen inhibitor - treatment of BPH symptoms, hair regrowth, Pregnancy category X
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Cardiac

Question Answer
digoxin/LanoxinCardiac glycosides - treatment of late stage heart failure
procainamide/ProcanbidSodium Channel blocker - Class I drug to treat dysrhythmias
propranolol/InderalBeta-adrenergic Antagonist - Class II drug to treat dysrhythmias
amiodarone/CordaronePotassium Channel blocker - Class III drug to treat dysrhythmias
verapamil/CalanCalcium Channel blocker - Class IV drug to treat dysrhythmias
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Anti-Infectives

Question Answer
penicillin GPenicillin antibiotic - narrow spectrum, bacteriocidal, short half-life, most common AE = allergic rxn
cefazolin sodium/AncefCephalosporin antibiotic - similar to PCN, classed by generations (5), may produce disulfiram-like reaction to ETOH
tetracycline/SumycinTetracycline antibiotic - broad spectrum, bacteriostatic, causes tooth discoloration if taken by pregnant/lactating women or children under 8
erythromycin base/E-mycinMacrolide antibiotic - narrow spectrum, safe alternative to PCN, resistant strains are becoming more common, metabolized and concentrated in liver
gentamicin base/GaramycinAmnioglycoside antibiotic - narrow spectrum, has postantibiotic effect (can remain in system up to 20 days after d/c), potential for oxotoxicity and nephrotoxicity
ciprofloxacin Hcl/CiproFluoroquinolone antibiotic - broad spectrum, classed by generations (4), over 50% have been d/c'd by FDA for safety concerns, potential for causing toxicity in many body systems
trimethoprim-sulfamethoxazole/Bactrim, SeptraSulfonamide antibiotic - broad spectrum, suppresses bacterial growth by inhibiting synthesis of folic acid, traditional drug of choice for UTI, can cause crystalluria in pts with renal impairment
isoniazidMycobacterial - drug of choice for TB but may be given other drugs concurrently for active disease (often rifampin), inhibits synthesis for mycolic acid - bacteriocidal for active disease, bacteriostatic for dormant
vancomycin/VancocinMiscellaneous antibiotic / Cell Wall Inhibitor - usually given IV, poorly absorbed orally
fluconazole/DiflucanAzoles antifungal - disrupts fungal cell membrane, Azoles are often drug of choice for superficial or subcutaneous infections (amphotericin B/Fungizone is the drug of choice for systemic)
chloroquineAntimalaria; - is used as chemoprophylaxis and to treat acute attacks or prevent relapses
metronidazole/FlagylNonmalarial protozoan drug - treats intestinal (and other) protozoans, drug of choice for giardiasis & trichomoniasis
acyclovir/ZoviraxHerpesvirus antiviral - used to lessen severity of acute herpes infection and to prolong latency (does not cure)
zidovudine/RetrovirHIV/AIDS antiviral - used to reduce related morbidity, restore/improve immunologic function, suppress viral load, prevent mother to child transmission (does not cure)
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Gastrointestinal

Question Answer
omeprazole/PrilosecPPI - blocks gastric acid secretion, treatment of PUD and GERD
ranitidine/ZantacH2-receptor Antagonist - suppresses gastric acid secretion, treatment of PUD and GERD
aluminum hydroxideAntacids - inactivates pepsin by binding with Hcl acid, neutralizes stomach acid, raising stomach pH; treats symptoms of PUD and GERD but does not promote healing
psyllium mucilloid/MetamucilBulk-forming laxative - helps prevent constipation, also helps absorb fluid and add bulk for diarrhea
diphenoxylate with atropine/LomotilOpioid antidiarrheal agent - most effective drug for controlling diarrhea (short term use only), slows peristalsis in colon, allows more fluid and electrolyte absorption
sulfasalazine/AzulfidineAnti-inflammatory - treatment of IBD, used to reduce acute symptoms, may be used with immunosuppressants.
prochlorperazine/CompazineAntipsychotic/antidopaminergic - used to treat nausea and vomiting, inhibits dopamine receptors in CTZ, often used for severe chemo-induced N&V
pancrealipase/Cotazym, PancreasePancreatic enzymes - replacement enzymes for chronic pancreatitis, are of pork origin (check if patient has pork allergies & religious customs)
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