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Nuclear medicine

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alapaj's version from 2017-05-29 12:40

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Question Answer
The physical half life of a radionuclide is the time it takesFor the nuclide to decay to one half of the original activity
Which of the following can be said regarding effective half-lifeIt is always shorter than both the physical and the biological half life
Which of the following is not a desirable characteristic of radionuclide use for imagingParticulate emission
In the event of a spill of 99mTc to clothes on should immediatelyRemove and store the clothes until they decay to backgroud
Which of the following measures absorbed dosesgray
The philosophy of the ALARA program is to keep the radiation doseAs low as reasonably achievable
Beta emitters are effective for therapy becauseThey can be used for imaging as well for therapy
What is the purpose of hydration and voiding after an injection for a boneTo reduce radiation dose in the bladder
Which of the following is a malignant bone diseaseEwing sarcoma
What is not an indication for a bone scanOsteoporosis
A bone scan showing relatively uniformly increased skeletal uptake of radiopharmaceutical with almost absent renal and bladder activity is usually referred to as aSuperscan
What are the common sites of bony metastasispelvis, spine, ribs
The advantage of bone scanning over plain radiography is/areEfficient for a multifocal trauma, bone must lose only a minimum of calcium before lesions are visible
Which of following agents will cross an intact bbb99mTc HMPAO
Which of the following agents is not commonly used for brain perfusionimaging with SPECT 99mTc DTPA
Akinesis refers toA lack of wall motion
Which of the following is not used to image the heart99mTc diphoshonate
Myocardial ischemia is determined byCoronary circulation is unable to couple with metabolic demand
In an asthmatic patient which of the following tests is contraindicatedExercise stress test
Dobutamine test should be used with caution inPatients with history of arrhythmia
In the early post-infarction period (<3 days), which test is more indicated to assess residual ischemiaDipyridamol or adenosine test
Why is it necessary to inject two doses of 99mTc sestamibi for a myocardial perfusion study including both stress and rest conditionsBc there is no redistribution of 99mTc sestamibi within the myocardium
What is the method of localization for the perfusion lung studyCapillary blockade
Increased risk of pulmonary embolism is associated withsmoking, use of oral contraceptives, recent surgery
Which radiopharmaceutical is commonly used to image cavernous haemangioma99mTc RBC
Clearance of 99mTc Mag3 is byTubular secretion
Indications for renal scanning with radionuclides includeAll;evaluation of space occupying lesions, asses function of native kidneys, allergy to iodinated contrast, asses load flow to transplanted kidneys
If after administration of furosemide, a patient still has activity in the renal calyces, there is probablyCollecting system obstruction
Preparation for captopril renography includesAll; ace inhibitors stopped, fasting to enhance absorption, well hydrated patient
Captopril is used whenThe patient is suspected of having renovascular hypertension
111In pentetreotide is asomatostatin analogue
Examples of the neuroendocrine tumor include All; pituitary adenoma, small cell lung cancer, neuroblastomas
The use of 131I for thyroid imagingIs typically only used when scanning the whole body for metastatic thyroid disease
The highest doses of therapeutic 131I are given to patients withThyroid cancer
About 90% of the thyroid secreted into the blood is in the form ofThyroxin
Which of the following are used to calculate the dose of 131I needed for administration in a patient with hyperthyroidismAll; weight of gland, percent of uptake, presence or absence of nodules
Which imaging technique is an absolute must in the diagnosis of thyroid diseaseUltrasound
Normal or increased radionuclide uptake in thyroid scintigraphy is observed inGraves disease
What is not a side effect radioiodine therapy of nontoxic goiterNeck tenderness
Which of the following is used in the treatment of Non-Hodgkin’s lymphoma90Y ibritumomab tiuxetan
Which of the following radionuclides is not a positron emitter14C
Which of the following has the shortest half-lifeRB82
Which of the following is true regarding 18FDGIt is taken up by a disease free myocardium
18FDG uptake can be present also ininflammation
The on site availability of a cyclotron is mandatory inIn all centers with a PET scanner
PET-FDG is helpful in defining therapeutic strategiesIn radiotherapy and chemotherapy
Physiological uptake of 18F-FDG is commonly seen inBrown fat and muscle in tense patients
The following are required before injecting 18F-FDGFasting for 6 hrs
At the present are available as hybrid machinesAll; PET-CT, SPECT-CT, PET-MRI
The main mechanism of detection in PET areCoincidence
Which of the following radioisotope used in palliative treatment of pain in malignant metastatic bone lesionSm-153 EDTMP
Which of the following radioisotope indicated for radiosynovetomy is interphalangeal jointsEr-169
The mechanism of localization of 18F-FDG is (one is false)Tumor specific
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difficult stuff

Question Answer
Which of following agents will cross an intact bbb99mTc HMPAO
Which of the following agents is not commonly used for brain perfusionimaging with SPECT 99mTc DTPA
Which of the following is not used to image the heart99mTc diphoshonate
In the early post-infarction period (<3 days), which test is more indicated to assess residual ischemiaDipyridamol or adenosine test
Which radiopharmaceutical is commonly used to image cavernous haemangioma99mTc RBC
Clearance of 99mTc Mag3 is byTubular secretion
The use of 131I for thyroid imagingIs typically only used when scanning the whole body for metastatic thyroid disease
If after administration of furosemide, a patient still has activity in the renal calyces, there is probablyCollecting system obstruction
Which of the following is used in the treatment of Non-Hodgkin’s lymphoma90Y ibritumomab tiuxetan
Which of the following is true regarding 18FDGIt is taken up by a disease free myocardium
18FDG uptake can be present also ininflammation
Physiological uptake of 18F-FDG is commonly seen inBrown fat and muscle in tense patients
Which of the following radioisotope used in palliative treatment of pain in malignant metastatic bone lesionSm-153 EDTMP
Which of the following radioisotope indicated for radiosynovetomy is interphalangeal jointsEr-169
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new stuff

Question Answer
C11 acetate choline used inprostate cancer
somatostatin used ininsulinoma
zevalin is used inlymphoma, malignant B cell, non hodkins
Sm-152 EDTMP is used inbone metastases
large joints90Y
small/medium jointsR-188
cells are most sensitive inM and G2 phase
cells are radioresistant inS phase
schochastic effectpropability of occurence increases with increased dose, no treshold
deterministic effectincrease in severity with increasing dose, treshold value
which nucleotide for paliative therapy doesnt emit beta particlesSn-117
annual dose for medical roffesional20mSv
annual dose genral in publis1mSv
isotope definitionnuclear nr same mass nr changed. same nr of protons, different nr of neutrons
minimal required iodine supply150 microgramc adult
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