Nitroglycerin (Nitrolingual, Nitrostat, Nitrobid, Tridil)

paramedic's version from 2017-08-28 00:13


Question Answer
Classification Vasodilator, Nitrate, Antianginal
Mechanism of ActionDecreases Myocardial O2 demand, Decreases preload/ after load, Decreases Peripheral Vascular Resistance, Increases Coronary Artery Dilation
IndicationsCardiac Induced Chest Pain (Angina, AMI) AND Acute Pulmonary Edema
Contraindications Hypersensitivity, BP < 90mmHg systolic, Patients who have taken ED drugs within 48 hours, Patients with increased ICP / Head Injury, Shock
Side EffectsHypotension/ Bradycardia, Nausea/ Vomiting, Rebound Hypertension, Tachycardia, Headache
Routes of AdministrationSL/ Trans-Dermal (TD)/ IVPB
Onset/ Duration1-3 mins. / 30-60 mins.
Adult DoseSL: 0.4 mg every 5 mins. X 3, TD: 0.5- 2 inches paste (TD), WPD: 10- 20 mcg/mins. (IVPB)
Pediatric DoseNot typically used for pediatrics
Additional info.Take blood pressure before and 5 mins. after NTG administration