Create
Learn
Share

NAPLEX

rename
jsuper512's version from 2016-08-30 03:24

Section

Question Answer
Drugs that leach into PVCTacrolimus
Temsirolimus
Teniposide
Cabazitaxel Two Tiny Tots Came Dressed In Elephant Pajamas
Docetaxel
Ixabepilone
Etoposide
Paclitaxel
Drugs requiring filtration during administrationAbatacept,
Abciximab,
Amiodarone (continuous infusion),
DigiFab,
Golimumab,
Infliximab,
Isavuconazonium,
Lipids,
Lorazepam,
Mannitol,
Phenytoin,
TPN,
Thiotepa
Drugs requiring filtration during preparationAmphotericin B (liposomal and lipid complex)
Protect from light during adminAnthracyclines,
decarbazine (protect tissue from light if extravasates),
Doxycycline, Epoprostenol (Flolan),
Micafungin,
Nitroprusside,
Pentamidine,
Phytonadione
Drugs with sorption issuesSufentanil,
Lorazepam,
Thiopental,
Insulin
Nitroglycerin,
Amiodarone
Carmustine
memorize

Hep

Question Answer
Lamivudine brand name and class; D-D; health riskEpivir (Epivir HBV) NRTI; Bactrim; pancreatitis
Adefovir brand name and classHepsera NRTI
Tenofovir brand name and class; D-DViread NRTI; didanoine and adefovir (Hepsera)
Entecavir brand name and class; counselingBaraclude NRTI; take on empty stomach 2 hr b4 or after meal
Telbivudine brand name and calss; D-DTyzeka NRTI; INF-alpha
NRTI class CrCl dosing< 50 mL/min
NRTI class big drug interactionRibavirin can inc. hepatotoxic effects --> lactic acidosis
SovaldiSofosbuvir
HarvoniSofosbuvir + ledipasvir
DaklinzaDaclatasvir
TechnivieParitaprevir / ritonavir / ombitasvir
Viekira PakParitaprevir / ritonavir / ombitasvir + dasabuvir
HCV 1a TxSofosbuvir + Daclatasvir (12 weeks)
Sofosbuvir + Ledipasvir (Harvoni) (12 weeks)
Sofosbuvir + Simeprevir (12 weeks)
Viekira Pak + ribavirin (12 weeks)
HCV 1b TxSofosbuvir + Daclatasvir (12 weeks)
Sofosbuvir + Ledipasvir (Harvoni) (12 weeks)
Sofosbuvir + Simeprevir (12 weeks)
Viekira Pak (12 weeks)
HCV 2 TxSofosbuvir + Daclatasvir (12 weeks)
Sofosbuvir + ribavirin (12 weeks)
HCV 3 TxSofosbuvir + Daclatasvir (12 weeks)
HCV 4 TxSofosbuvir + Ledipasvir (Harvoni) (12 weeks)
Technivie + ribavirin (12 weeks)
Sofosbuvir + ribavirin (24 weeks)
HCV 5-6 TxSofosbuvir + Ledipasvir (Harvoni) (12 weeks)
memorize

ABx brand / generic

Question Answer
UnasynAmp/Sulbactam
TimentinTicarcillin + clav
Ancef, KefzolCefazolin (IV/IM)
KeflexCephalexin (PO)
Ceftin, ZinacefCefuroxime (PO/IV/IM)
CefotanCefotetan (IV/IM)
OmnicefCefdinir (PO)
RocephinCeftriaxone (IV/IM)
ClaforanCefotaxime (IV/IM)
Fortaz, TazicefCeftazidime (IV/IM)
AvycazCeftazidime + avibactam (IV/IM)
ZerbaxaCeftolozane/tazobactam (IV)
MaxipimeCefepime (IV/IM)
TeflaroCeftaroline fosamil (IV)
DoribaxDoripenem (IV)
PrimaxinImipenem/Cilastatin (IV)
MerremMeropenem (IV)
InvanzErtapenem (IV/IM)
AzactamAztreonam (IV)
CaystonAztreonam (inh)
CiloxinCipro (opth)
CetraxalCipro (otic)
ZymaxidGatifloxacin (opth)
AveloxMoxiflox (IV/PO)
MoxezaMoxi (opth)
VigamoxMoxi (opth)
FactiveGemifloxacin (PO)
XtoroFinafloxacin (otic)
BiaxinClarithromycin
AdoxaDoxycycline
AtridoxDoxy
DoryxDoxy
MonodoxDoxy
OraceaDoxy
VibramycinDoxy
MinocinMinocycline
SolodynMinocycline
VibativTelavancin (IV)
OrbactivOritavancin (IV)
DalvanceDalbavancin (IV)
CubicinDaptomycin (IV)
ZyvoxLinezolid (PO/IV)
SivextroTedizolid (IV/PO)
SynercidQuinupristin/Dalfopristin
TygacilTigecycline (IV)
KetekTelithromycin (PO)
CleocinClindamycin (IV/PO)
DificidFidaxomicin (PO)
XifaxanRifaximi (PO)
MonurolFosfomycin (PO)
memorize

HIV opportunistic infection Prophylaxis

Question Answer
CD4 < 200pneumocystis pneumonia (PCP)
Pneumocystis pneumonia (PCP) Preferred PxBactrim DS 1 tab PO daily
CD4 < 100Toxoplasma gondii
Toxoplasma gondii Preferred PxBactrim DS 1 tab PO daily
CD4 < 50Mycobacterium avium complex (MAC)
Mycobacterium avium compled (MAX) Preferred PxAzithromycin 1200 mg PO QW -OR-
Clarithromycin 500 mg po BID -OR-
Azithromycin 600 mg PO twice weekly
Cytomegalovirus (CMV) TxValganciclovir or Ganciclovir
Cytomegalovirus (CMV) secondary PxValganciclovir
Cryptococcal meningitis TxAmphoB deoxycholate + flucytosine
Cryptococcal meningitis secondary PxFluconazole low dose
Mycobacterium avium complex (MAC) TxClar or Azith + Ethambutol
Mycobacterium avium complex (MAC) secondary PxClar or Azith + Ethambutol
Pneumocystis pneumonia (PCP) TxBactrim +/- prednisone or methylprednisolone x 21 days
Pneumocystis pneumonia (PCP) secondary PxBactrim or
dapsone or
[dapsone + pyrimethamine] or
atovaquone or
INH pentamidine
Toxoplasmosis meningoencephalitis TxPyrimethamine + sulfadiazine
Toxoplasmosis meningoencephalitis secondary PxPyrimethamine + sulfadiazine (reduced dose)
memorize

ART drugs brand / generic

Question Answer
EpzicomAbacavir (NRTI) + Lamivudine (NRTI)
TriumeqAbacavir (NRTI) + Lamivudine (NRTI) + Dolutegravir (INSTI)
TruvadaEmtricitabine (NRTI) + Tenofovir (NRTI)
CombivirLamivudine (NRTI) + Zidovudine (NRTI)
TrizivirAbacavir (NRTI) + Lamivudine (NRTI) + Zidovudine (NRTI)
AtriplaEmtricitabine (NRTI) + Tenofovir (NRTI) + Efavirenz (NNRTI)
CompleraEmtricitabine (NRTI) + Tenofovir (NRTI) + Rilpivirine (NNRTI)
StribildEmtricitabine (NRTI) + Tenofovir eisoproxil fumarate (NRTI) + Elvitegravir (INSTI) + Cobicistat (CYP 3A4 I)
GenvoyaEmtricitabine (NRTI) + Tenofovir alafenamide (NRTI) + Elvitegravir (INSTI) + Cobicistat (CYP 3A4 I)
Protease inhibitors names end in-navir
Integrase strand transfer inhibitors (INSTIs) names end in-tegravir
NRTI class BBWlactic acidosis and severe hepatomegaly with steatosis
PI-Based regimen per guidelinesDarunavir + Ritonavir + Emtricitabine + Tenofovir
memorize

Single Drug ARTs brand / generic (class)

Question Answer
ZiagenAbacavir (NRTI)
VidexDidanosine (NRTI)
EmtrivaEmtricitabine (NRTI)
EpivirLamivudine (NRTI)
ZeritStavudine (NRTI)
VireadTenofovir (NRTI)
RetrovirZidovudine (NRTI)
RescriptorDelavirdine (NNRTI)
SustivaEfavirenz (NNRTI)
IntelenceEtravirine (NNRTI)
ViramuneNevirapine (NNRTI)
EdurantRilpivirine (NNRTI)
PrezistaDarunavir (PI)
ReyatazAtazanavir (PI)
LexivaFosamprenavir (PI)
CrixivanIndinavir (PI)
KaletraLopinavir (PI) + Ritonavir (PI)
ViraceptNelfinavir (PI)
NorvirRitonavir (PI / CYP 3A4, 2D6 I)
InviraseSaquinavir (PI)
AptivusTipranavir (PI)
TivicayDolutegravir (INSTI)
VitektaElvitegravir (INSTI)
IsentressRaltegravir (INSTI)
SelzentryMaraviroc (CCR5)
FuzeonEnfuvirtide (Fusion Inhib)
memorize