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MSK Tumors

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theyak89's version from 2016-06-02 18:37

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20-40 years old, epiphyseal end of long bones. Aggressive, often around knee. Soap bubble on x-ray. Multinucleated giant cellsGiant Cell tumor/osteoclastoma (benign)
Most common benign bone tumor. Males <25. Mature bone with cartilaginous cap.Osteochondroma (benign)
10-20 year old, and >65 yo. Associated with Paget disease, infarcts, familial retinoblastom, Li-Fraumeni syndrome, p53 mutationOsteosarcoma (malignant)
Bimodal distribution, Metaphysis of long bones, often knee. Codman Triangle and sunburst patternOsteosarcoma (malignant)
Males <15 years old. Diaphysis of long bones, pelvis, scapula, ribs. Ewing Sarcoma
Anaplastic small blue cell malignant tumor. Extremely aggressive. Onion skin appearance. t(11;22) translocationEwing Sarcoma
Cartilaginous tumor, men 30-60, located in pelvis, spine, scapula, humerus, tibia, femurChondrosarcoma
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