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Morphological Changes in MI (DONT MESS THIS UP)

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omranalzobaidi's version from 2015-11-29 14:45

Histo

Times from InfarctionGross ChangesMicroscopic ChangesComplications
Less than 4 hrsnonewavy fibrous , contraction bandsshock massive infarction , CHF and arrythmia .
4-24 hoursdark discolorationcoagulative necrosisarrhythmia
1-3 daysyellow pallor , Hyperemianeutrophilsfibrinous pericarditis , chest pain with friction rub
4-7 daysyellow pallormacrophages ( weakest point of the ischemia )rupture of ventricular free wall, interventricular septum (temponade) or papillary muscle (new murmer )
1-3 weeksred border emerges as granulation tissue enters from edge of infarctsgranulation tissue with plump fibroblasts ,collagen and blood vessels
monthswhite scarfibrosisaneurysm, mural thrombus, Dressler syndrome (antibodies against own pericardium)
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