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Monoclonal antibodies

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visikuya's version from 2015-11-12 22:48

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Question Answer
trastuzumab usesbreast CA, + mets.
trastuzumab ADRcardiotoxic, careful with anthrocyclines
bevacizumab usesMETS-colon,lung, brain
bevacizumab ADRHTN, Gi bleed, thromboembolitic event
Bevacizumab MOAbings VEGF, prevents angiogenesis
cetuximab uses[check KRAS mutation first] METS colon, head/neck CA
cetuximab ADRhypersensitivity rxn; acineform rash
panitumumab usesMETS colon
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