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Midterm 1 Bild 12 Lecture 3

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iamjuliesan23's version from 2017-02-02 00:02

Section 1

Question Answer
How many neurons are in the human Brain?100,000,000,000
Information flows across neuron?Electircal synapses: electrical coupling of two neurons.
Chemical synapses..The presynaptic neuron releases special chemicals neurotransmitters to communicate with the postsynaptic neuron.
What are synaptic vesicles? contain neurotransmitters
s
memorize

Section 2

Question Answer
Neurotransmitter release step oneAP reaches axon terminal
step 2depolarization opens Ca2+ channels
step 3Ca2+ channels flows in axon terminal
step 4Synaptic vesicles fuse in membrane
step 5Neurotransmitters in vesicles released into synaptic cleft
memorize

Section 3

Question Answer
Synaptic vesicle fusionN. release SNARE proteins
step 2Ca2+ voltage gated channels changes the conformation of SNARE proteins
step 3Neurotransmitter inside vesicle gets released into the synaptic cleft
memorize

Section 4

Question Answer
Bernard Katz 'all or nothing' AP, nobel prize 1970
Synaptic vesicles they are recycled and re-packed with neurotransmitters.
Pump of Neurotransmitters synaptic cleft into presynaptic terminal
2nd P.Ncytosol to synaptic vesicles
memorize

Section 5

Question Answer
Glutamate receptor ionsNa+ channels
Is it depolarize or hyperpolirizeDepolarize
Is it excitatory or inhibitory? Excitatory
memorize

Section 6

Question Answer
how are action potentials generated? enough synaptic excitation to open voltage-gated sodium channels.
Synaptic integration.one synapse is not enough for AP in postsynaptic
Spatial summation.multiple synapses
Temporal Summation single synapse
memorize

Section 7

Question Answer
GABA Receptor ionsCl- Channels
They are Inhibitory
which makes postsynaptic neuron fire fewer action potentials
memorize