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robbypowell's version from 2016-02-05 17:21

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Question Answer
Ritter's disease is a _______ mediated diseaseExotoxin (A & B)
How long lasting is immunity to staph food poisoning?short-lived
Staph food poisoning is a ______ mediated diseasetoxin
Panton-Valentine leukocidin is a virulence factor found in which bacteria?MRSA
Multi-layer peptidoglycan is found in cell walls of gram _____positive
purpura filimans is a virulent form of...Toxic Shock syndrome
Techoic acid is a major component of cell wall in gram _____ bacteriapositive (not negative)
staphylococcal toxis shock is caused by staphylococcus ______aureus
Legionella is gram _____Negative
Is Legionella acid fast?No
bacteria associated with pools of stagnant waterLegionella pneumophilia
bacteria associated with dental water linesLegionella pneumophia
does Legionella grow on traditional agar?No
requirement for plate growth specific to Legionella pneumophiaCystein (also Iron)
Azithromycin (a Microlide) and Levofloxacin (a Fluroquinolone) are used to treat what?Legionella
This family is known for being a chain of spherical bacteriaStreptococcus
Streptococcus is gram ____Positive
is Legionella motile?yes
Is streptococcus motile?no
does streptococcus form spores?no
what is the metabolic classification of streptococcus?Facultative anaerobe
what is the food that Legionella eat?amino acids
what is the food that Streptococcus eats?carbohydrates
streptococcus is Catalase ____negative
streptococcus like to grow with a lot of carbon in the medium... this is bc they are ______capnophilic
what test is used to distinguish between strep and staph?Catalase test (strep is negative)
Ludwig's Angina is caused by what type of bacteria?Streptococcus
Necrotizing fascitis is caused by what type of bacteria?Streptococcus
Acute Glomerulonephritis and Rheumatic fever are associated with what bacteria?Strep (nonsuppurative infections)
CAMP test is used for ...S. agalactiae
They are green when they grow in culture. These are group C and G.Viridans Streptococci
most virulent member of Viridans StreptococciStreptococcus pneumoniae
Small, encapsulated lancet-shaped cells arranged in pairs and short chains (which species)Streptococcus pneumoniae
2 forms of techoic acid are in the cell wall of what species?Streptococcus pneumoniae
what marker is unique to the cell wall of Streptococcus pneumoniaePhosphocholine
S. Pneumoniae is more deadly with or without a capsule?with!!! (S type is with capsule)
Optochin test and Bile solubility test are for testing what bacteria?Streptococcus pneumoniae
Antigen detection on S. pneumonia has a 100% sensitivity for what antigen?Pneumococcal C polysaccharide
best treatment for any streptococcal infectionpenicillin
Enterococci grow on high concentrations of ____ and bile saltsNaCl
Normal colonists of human large intestineEnterococci
Oldest bacteria detected on earthMycobacterium
Is Mycobacteria gram negative or gram positive?NEITHER
What type of bacteria causes tuberculosis and leprosy?Mycobacteria
what bacteria type is number one killer in the world?Mycobacteria
more than three weeks of cough, fever, night sweats and unexpected weight loss are symptoms of what disease?Tuberculosis (caused by mycobacterium)
Tuberculosis is responsible for _____ deaths a year1.5 million
Sirturo (bedaquiline) is a drug to treat what?Drug resistant Tuberculosis
Is Mycobacterium acid fast?yes
Do mycobacteria divide fast or slow?Slow
What layer in mycobacteria cell walls sets them apart from gram - and gram + walls?MAPc layer (Mycolic acid, Arabinogalactan, Peptidoglycan)
Mycobacteria have high ___ & ____ in their DNACytosine & Guanine
Runyon classification is used for what group?Non-Tuberculoud Mycobacteria
GHONS BODY associated with what disease?Tuberculosis (mycobacteria)
leading killer of people who are HIV infectedTuberculosis (mycobacteria)
Ziehl-Neesen is a test used for what diseaseTuberculosis (mycobacteria) (also AFB testing... whatever it is)
calcification of primary focus/LN in lungs is sign of what disease?tuberculosis (mycobacteria)
What is the only organism that is coagulase positive?S. Aureus
how do they do a skin test for TB?PPD (purified protein derivative)
ESAT-6 & CFP-10 immunoassays are used to test for what type of bacteria?Mycobacteria (TB)
INAH, Rifampicin, Ethambutol & Pyrazinamide are used to treat what?Tuberculosis
what species Staph associated with UTI in young women?Saprophyticus
best tx for hospitalized MRSA patientsIV vancomycin
secondary structure of staphylococci growthgrow in clusters (like clusters of grapes)
Protein A is found on the surface of ...Coagulase positive S. Aureus
Lancefield streptococcal grouping is based on ______ propertiesserologic
streptococcus grown in lab... 2ndary and primary structurelong chains, spherical cocci
M. protein is associated with what species?Strep pyogenes
what are two mediators of Strep progenies invasion of epithelial cells?F protein and lipotechoic acid
only streptococci carrying group B antigen...agalactiae
most important virulence factor for Strep agalactiaepolysaccharide capsule
what strep causes pharyngitis?Pyogenes
is rheumatic fever suppurative or non-suppurative?non
Neisseria is gram ____negative
Gonorrhea and Meningitidis are what type of bacteria?Neisseria (gram -, cocci)
What type of metabolism for Neisseria?Aerobic
what is the 2ndary morphology of Neisseria, primary?pairs, cocci
Neisseria are catalase ____positive
Neisseria are oxidase ____positive
what type bacteria are associated with pilli?Neisseria (long are pathogenic) (gonorrhea, meningitidis)
staphylococci are are gram _____Positive
what type of agar plate is gonorrhea grown on?chocolate agar
only carb that gonorrhea can oxidize to acidglucose
All Staphylococci are catalase ____positive
staph aureus in blood will cause a coagulative clot... this is due to _____coagulase
coagulase positive bacteria speciesS. Aureus
does staph aureus have capsule?yes
slime layer is associated with what type bacteria?staphylococci
Protein A assoc with what species?S. Aureus
Protein A works by binding to _____ or _____Fc or Fab
Panton-Valentine leukocidin assoc with what species?staph aureus (mrsa, i think)
super antigen induced toxic shock is a mechanism of uncontrolled _____ cellsT cells
protein most commonly associated with toxic shock (super antigen)TSST1
gene that confers Methicillin resistance to S. AureusMecA
antibiotic for MRSA useVancomycin
memorize

staph

Question Answer
staphylococci are are gram _____Positive
All Staphylococci are catalase ____positive
staph aureus in blood will cause a coagulative clot... this is due to _____coagulase
what allows staph to adhere to mucosal membranes?techoic acid
virulence factor of s. aureus that prevents phagocytosisProtein A
Protein A works by binding to _____ or _____Fc or Fab
localized form of SSSS with no Nikolsky sign presentBullous impetigo
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Neisseria

Question Answer
what % of people carry Neisseria?2%
Neisseria is gram ____negative
2 important examples of NeisseriaGonorrhea & Meningitidis
What type of metabolism for Neisseria?Aerobic
which pilli of neisseria are associated with pathogenicity?LONG pill
Neisseria produce acid by _____ not _____oxidation, NOT fermentation
what feature of neisseria is "–important for variation, adherence, entry by nucleating actin which modifies the cytoskeleton, protection from host"?Porins (protein1-5 or Pro, Opa, Opc)
what is contained in the capsule-like structure of Gonorrhea (Neisseria)?MW Polyphosphates
Gonorrhea is sensitive to _____ and needs additional ____ to grow in mediadrying; CO2
what type of agar plate is gonorrhea grown on?chocolate agar
only carb that gonorrhea can oxidize to acidglucose
on a phenol red test... when media becomes more acidic it becomes more _____yellow
rx treatment for gonorrheaCeftriaxone (single IM dose) & Azithromycin (single oral dose) or Doxycycline (2x day for 7 days)
because of resistance... the CDC no longer recommends ______ for treatment of gonorrheaFluoroquinolones
probability of acquiring gonorrhea from infected woman ____; infected man ____20-25%; 40-70%
which is more contagious.... gonorrhea or HIV?Gonorrhea (by a factor of at least 100)
Sharply localized white or yellow-white patch on oral mucosa could be what std?gonorrhea
example of encapsulated Neisseria speciesMeningitidis
phenol red test results for Meningitidisglucose & maltose (gonorrhea is only glucose)
what group of children is especially susceptible to N. Meningitidis?2-10 yo w/ cochlear implants
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matching Mycobacteria drugs with their target

Question Answer
Mycelia acids (target)Isoniazid
Membrane acidificationPyrazinamide
RNA polymerase (Beta subunit)Rifampicin
ATP synthaseR207910
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mycobacteria

Question Answer
Oldest bacteria detected on earthMycobacterium
Is Mycobacteria gram negative or gram positive?NEITHER
What type of bacteria causes tuberculosis and leprosy?Mycobacteria
what bacteria type is number one killer in the world?Mycobacteria
more than three weeks of cough, fever, night sweats and unexpected weight loss are symptoms of what disease?Tuberculosis (caused by mycobacterium)
Tuberculosis is responsible for _____ deaths a year1.5 million
Sirturo (bedaquiline) is a drug to treat what?Drug resistant Tuberculosis
Is Mycobacterium acid fast?yes
Do mycobacteria divide fast or slow?Slow
What layer in mycobacteria cell walls sets them apart from gram - and gram + walls?MAPc layer (Mycolic acid, Arabinogalactan, Peptidoglycan)
Mycobacteria have high ___ & ____ in their DNACytosine & Guanine
Runyon classification is used for what group?Non-Tuberculoud Mycobacteria
List three examples of Rapidly growing non-tuberculoid mycobacteriachelonae, fortuitum, abscessus
GHONS BODY associated with what disease?Tuberculosis (mycobacteria)
how long is the incubation time for tuberculosis?1-3 months
leading killer of people who are HIV infectedTuberculosis (mycobacteria)
Ziehl-Neesen is a test used for what diseaseTuberculosis (mycobacteria) (also AFB testing... whatever it is)
calcification of primary focus/LN in lungs is sign of what disease?tuberculosis (mycobacteria)
What is the only organism that is coagulase positive?S. Aureus
how do they do a skin test for TB?PPD (purified protein derivative)
ESAT-6 & CFP-10 immunoassays are used to test for what type of bacteria?Mycobacteria (TB)
INAH, Rifampicin, Ethambutol & Pyrazinamide are used to treat what?Tuberculosis
memorize

Legionella

Question Answer
Legionella is gram _____Negative
Is Legionella acid fast?No
Is Legionella aerobic, anaerobic or a facultative anaerobe?Aerobic
Does Legionella have spores?No
What is the major species of Legionella? What is the serogroup responsible for most infections?Legionella Pneumophila
T/F: Legionella pneumophilia can be contracted from person to person contactFalse (only environment to person)
pools of stagnant water associated with what bacteria?Legionella pneumophia
what are the 2 different diseases caused by Legionella pneumophilaLegionairre's disease (fatal, with pneumonia) & Pontiac fever (milder, no pneumonia)
What is the mechanism of legionaire's disease?Taken in by phagosome, but phagosome cannot acidify... so becomes sanctuary for growth and division
What type of media can Legionella be plated on?charcoal yeast extract agar
best way to test for legionellafatty acid profiling (also antigen detection in urine)
memorize

Streptococcus

Question Answer
T/F: Streptococcus can spread from the oral cavity to the rest of the bodyTrue
T/F: Streptococcus from the oral cavity can not set up in other parts of the bodyFalse
What is the phylum of Streptococcus?Firmicutes
what is the food that Streptococcus eats?carbohydrates
streptococcus is Catalase ____negative
streptococcus like to grow with a lot of carbon in the medium... this is bc they are ______capnophilic
which hemolytic classification completely lyses blood cells?Beta
which hemolytic classification is semi-capable of lysing blood cells?Alpha
which hemolytic classification cannot lyse blood cells?Gamma
what type of medium is used to test for Hemolytic typing of strep?Sheep's blood agar
screening of pregnant women is used to look for what group of strep?Group B
What species strep is known for its fast growth?Pyogenes
M protein (pyogenes?) interacts with what to give resistance to complement system?Fibrinogen
3 toxins associated with S. pyogenesSPE (super antigen), Streptolysin S, & Streptolysin O
best method for identifying strepMicroscopic methods (also DNAase test)
The only species that carries group B antigensS. agalactiae
Streptococcus agalactiae colonize where?lower GI and GU tracts
what substance on S. agalctiae inhibit the immune system?Sialic acid residue
what test is very specific for S. agalactiae?CAMP test
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