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Microbio

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tapadebe's version from 2018-04-16 06:09

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S. pyogenes direct infectionpharyngitis (strep throat), necrotizing fasciitis (tissue invasion enzymes), scarlet fever (rash from in to out), TSS (bacremic with evidence of fasciitis)
S. pyogenes antibody-mediated infection-rheumatic fever = TYPE II HYPERSENSITIVITY RXN due to M protein (Rhubarb Pie): *M protein Abs cross-react with heart valves*
-glomerulonephritis: Ag/Ab complexes deposited
S. agalactiaeneonatal meningitis, pneumonia, sepsis
EnterococcusUTI
S. viridans (2 + two buzzwords)"V"iridans = "V"ery sticky
- dental caries (PROPHYLACTIC ABX BEFORE DENTIST)
- subacute bacterial endocarditis (STICKS TO PROSTHETIC VALVES in pts with VALVE PROBLEMS)
S. pneumoniae (4 + buzzword)-pneumonia (RUSTY SPUTUM vs. bright red jelly = Klebsiella)
-OTITIS MEDIA
-meningitis (adults)
-sepsis
S. aureus toxin mediated (3)gastroenteritis, TSS (MTSS/tampons), scalded skin syndrome (exfoliative toxin)
S. aureus direct invasion mediated (3)pneumonia, *meningitis, *osteomyelitis (children), *acute endocarditis, septic arthritis, skin infection, sepsis, UTI
S. epidermidis (4 + generalization)prosthetic joint infection, IV sepsis, catheter UTI, ENDOCARDITIS from prosthetic heart valves *STUFF THAT GETS STUCK INTO YOU AT HOSPITAL; i.e. mostly nosicomal*
S. saprophyticus (1 + buzzword)UTI; leading cause in *NEWLY SEXUALLY ACTIVE FEMALES*
B. anthracis (3)- painless black ulcer on skin with central necrosis (ESCHAR)
- pulmonary hemorrhage, WIDENED MEDIASTINUM
- abdominal pain/ bloody diarrhea (rare)
B. cereusfood poisoning
M. tuberculosis (two stages)1º: Initially non-specific, then affects lungs – proceeds with either resolution or progression (reactivation or miliary)
• Granuloma (asymptomatic); Xray or PPD for definitive dx. Bacteria can be dormant in this stage.
• Reactivation or disseminated/systemic (MILIARY)

Post-1º: Cavitary lesions with bloody sputum (Cavitary disease)
M. leprae (2 + buzzword)1. Tuberculoid: Strong cell-mediated response = POSITIVE LEPROMIN SKIN TEST (delayed HS rx) = HYPOPIGMENTED SKIN MACULES (buzz) = few invasive org.
2. Lepromatous: Weak cell-mediated; strong anti-body = NEGATIVE LEPROMIN = lots of invasive org. NASAL MUCOSA INVOLVED, NERVE DAMAGE – DISFIGURING SKIN LESIONS
C. botulinumcranial nerve palsies, muscle weakness, respiratory paralysis
C. tetanimuscle spasm, lockjaw, risus sardonicus, respiratory paralysis
C. perfringensgas gangrene
C. difficilepseudomembranous colitis
C. diphtheriae (3 + buzzword)• sore throat/exudative pharyngitis (PSEUDOMEMBRANE)
- systemic complications if you try to pull off pseudomembrane.
• BULL NECK
• myocarditis (AV block) and recurrent laryngeal n. palsy (BOTH TOXIN MEDIATED)
Listerianeonatal meningitis, pneumonia, sepsis
N. meningitidismeningitis (teens), DIC, waterhouse-friderichsen syndrome
Actinomycesoral/ facial abscesses
N gonorrhoaeurethritis, PID, bacteremia (septic arthritis, rash); ophthalmia neonatorum (1st 5 days after birth)
E. colineonatal meningitis; UTI; hospital acquired pneumonia/ sepsis; diarrhea
K. pneumoniae (buzzword)pneumonia (necrotic destruction of alveolar spaces), bloody sputum/CURRANT JELLY (common in alcoholics)
Shigellabloody diarrhea
S. typhityphoid fever (fever, abd pain, hepatosplenomegaly, ROSE SPOTS on abdomen); intestinal PERFORATION; osteomyelitis (HbS patients)
Y. enterocoliticagastroenteritis
V. choleraesevere RICE-WATER STOOL (no pus)
C. jejunibloody diarrhea
H. pyloriHYPERCHLORHYDRIA (decreased acid), GASTRIC ANTRUM, duodenal ulcers; chronic gastritis
BacteroidesGI tract, pelvic, lung abscesses
Pseudomonas (3)-CYSTIC FIBROSIS (can't clear pseudomonas)/PULMONARY INFECTION
-burn infection, hot tub folliculitis, endocarditis, pneumonia, sepsis, malignant otitis externa, UTI, diabetic osteomyelitis
-Long term catheter
Acinetobacterhospital acquired pneumonia, UTI
H. influenzae type BUNVACCINATED CHILDREN/UNKNOWN (DROOLING, HUNCHED OVER)
meningitis (children), *acute epiglottitis*, septic arthritis (infants), sepsis, pneumonia
H. influenzae nontypeable*otitis media*, sinusitis
H. ducreyichancroid/PAINFUL GENITAL ULCER (vs. syphillus)
B. pertussislow grade fever, runny nose --> intense cough with whoop
Legionellapontiac fever (headache, myalgias, fatigue); legionnaire's disease (pneumonia, fever, cough)
Y. pestis (2)-hot, swollen lymph nodes, high fever, conjunctivitis; sepsis, pneumonia (bubonic plague)
-PSEUDOAPPENDICITIS
Borrelia recurrentisrecurrent fever
Chlamydia trachomatis; types A-Cconjunctivitis, corneal scarring, blindness
Chlamydia trachomatis; types D-KCORNEAL ULCERATION, NO CULTURE: urethritis, cervicitis, PID, epididymitis, prostatitis
Chlamydia trachomatis; types L1-L3lymphogranuloma venereum
Chlamydia pneumoniaeatypical pneumonia
R. rickettsiifever, conjunctival injection, severe headache, rash OUTSIDE IN (wrists, ankles --> generalized)
R. prowazekiiepidemic typhus (fever, headache, rash, delirium, extremity gangrene)
R. typhiendemic typhus (fever, headache, rash)
Borrelia burgdorferiLyme disease (erythema chronicum migrans --> Bell's palsy, peripheral neuropathy; heart block; arthritis --> chronic arthritis, encephalopathy)
Leptospiraflu-like symptoms; Weil's disease (renal failure, hepatitis-jaundice, hemorrhage)
V. parahaemolyticusSelf-limiting gastroenteritis
•Most common cause of gastroenteritis in Japan and SE Asia
B. recurrentisRELAPSING INTERVALS (due to antigenic variation)
Leptospira interrogans (3)Jaundice, uveitis, renal failure
Interrogate the JURORe
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