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Lipoprotein functions

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coleresi's version from 2017-12-08 18:08

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Question Answer
ChylomicronDelivers dietary TGs to peripheral tissue. Delivers cholesterol to liver in form of chylomicron remnant. Secreted by intestinal cells.
VLDLDelivers hepatic TGs to peripheral tissue. Secreted by liver.
IDLFormed by degradation of VLDL. Delivers triglycerides and cholesterol to liver.
LDLDelivers hepatic cholesterol to peripheral tissues. Formed by hepatic lipase modification of IDL in peripheral tissue. Taken up by target cells via receptor- mediated endocytosis.
HDLMediates reverse cholesterol transport from periphery to liver. Acts as a repository for apoC and apoE (which are needed for chylomicron and VLDL metabolism). Secreted from both liver and intestine.
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