Lecture 6

kshinsky's version from 2018-04-02 17:15


Question Answer
virionvirus before it enters host cel
characteristics of viruslack membrane, capsid, envelope
envelopephospholipid membrane
capsidprotein coat
capsids made up of capsomeres
genetic material of virusssDNA, dsDNA, ssRNA, dsRNA, linear, severe molecules
bacteriophagevirus that infects bacteria
naked virushas no enevelope
enveloped virionacquired from host cell and has glycoproteins that appear spike like
viral reproductionattachment, entry, synthesis, assembly, release
lysogenic replicationbacteriophage enters bacterial cell, inserts DNA and remains inactive
lytic not dormant
temperate phagebacteriophage that does not immediately kill the cell
replication of animal virusdependent on chemical attraction
steps of replication of animal virusentry and uncaring, direct penetration, membrane fusion, endocytosis
dsDNA replicationmRNA transcribed form viral DNA and sent to cytoplasm where ribosomes create capsoeres, capsomeres reenter nucleus where new virions assemble. herpes, HIV
ssDNAno need to uncoil, RNA polymerase synthesizes mRNA complimentary to the viral ssDNA, cellular ribosomes translate proteins. ex: parvovirus
reverse transctiptionRNA to DNA, ex HepB
retroviruspostive sense ssRNA, they need reverse transcriptase
+ssRNAact directly as mRNA and converted in polypeptides
-ssRNA uses RNA dependent RNA transcriptase, transcribes neg to pos
dsRNAonly pos strand will be used fo the transcription and translation, used for protein synthesis
assembly and release envelope virusby budding
assembly and release nakedby exocytosis or lysis
neoplasiatumor, uncontrolled cell division
viriodplant virus, small, ssRNA infectious in plants
prionsinfectious particle that lacks nucleic acid and replicated by converting normal proteins into new prions, ex: mad cow, creutzfeld jakob
prions characteristicscannot be killed by normal sterilization

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