ephender's version from 2015-06-07 16:01

Section 1

Question Answer
Anti Centromere AbCREST
Anti desmoglein (epithelial) abPemphigus Vulgaris - Blister
Anti Glomerular Basement membrane abGoodpasture syndrome - glomerulonephritis & hemoptysis
Anti histone abDrug Induced Lupus (SHIPP- Sulfa, Hydralazine, INH, Phenytoin, Procanamide)
Anti IgG abRheumatoid Arthritis( systemic inflammation, joint pannus, boutonniere deformity)
AMAs (anti mitochondrial)Primary Biliary Cirrhosis (female, cholestasis, portal HTN)
MPO-ANCA/ p- ANCAMicroscopic polyangiitis & Churg Strauss syndrome
PR3-Anca/c-ANCAgranulomatosis with polyangiitis
ANAs: anti smith & anti-dsDNASLE Type III HS
AntiplateletIdiopathic Thrombocytopenic Purpura
Anti Topoisomerase Diffuse Systemic Scleroderma
Anti Transglutaminase/ anti gliadin/ anti endomysial Celiacs (diarrhea, distention, weightloss)
Apple Core lesion on Abdominal XrayColorectal Cancer - Left Side
Azurophili peroxidase + granular inclusions in granulocytes and myeloblastAuer rods (AMLE, promyelocytic M3 type)
Bacitracin SensitiveStrep Pyogenes GAS
Bacitracin ResistantStrep Agalactiae GBS
Bamboo SpineAnkylosis Spondylitis (chronic inflammatory arthritis; HLA b27)
Basophilic Nuclear Remnants in RBCsHowell Jolly Bodies (splenectomy/ nonfunctioning spleen)
Basophilic Stippling of RBCsLead poisonin or sideroblastic anemia
Blood tap on LPSubarachnoid Hemorrhage
Boot Shaped Heart on XRAYTeratology of Fallot, RVH
BRanching gram-positive rods with sulfur granulesActinomyces Israelii
Bronchogenic apical lun tumor on imagingPancoast tumore (supresses sympathic ganglion and causes Horners syndrome
Brown Tumor of the boneHyperparathyroidism or Ostitis Fibrosa Cystica (deposited hemosidering from hemorrhage gives brown color
cardiomegaly with apical atrophyChagas (trypanosoma cruzi)
Cellular crecents in bowman spaceRapidly progressive crecentic glomerulonephritis
chocolate cyst of ovaryedometriosis of ovary
circular grouping of dark tumor cells surrounding pale neurofibrils)Homer Wright Rosettes (Neuroblastoma, medulloblastoma, retinoblastoma)
Pseudomonas in lungcysitic fibrosis (AR CFTR gene --> fat soluble vit deficiency & mucus plugs
decrease AFP in amniotic fluidDowns Syndrome Trisomy 21
Degeneration of dosal column nervesTabes Dorsalis (syphilis), Subactue Combined Degeneration (dorsal colums and lateral corticospinal tracts)
Depigmentation of Neurons in Substantia NigraParkinsons Disease (basal ganglia disorder: rigidity, resting tremor, bradykinesia)
Desquamated epithelium casts in sputumCurschman Spiral (bronchial asthma; can result in wholed mucus)
Disarrayed Granulosa Cells in Eosinophilic FluidCall-Exner Bodies (granulosa-theca cell tumor of the ovary)
Enlarged cells thyroid cells with ground glass nucleiOrphan Annie eyes Nuclei (papillary carcinoma of thyroid)
Eosinophillic Cytoplasmic Inclusion in Liver CellsMallory Body (alcoholic liver disease)
Eosinophillic Cytoplasmic Inclusion in Nerve CellsLewy Body (parkinson disease)
Dysplatic squamous cercial cells with nuclear enlargementKoilocytes (HPV: predisposes to cervical cancer)
Eosinophillic globules in liverCouncilman Body (toxic or viral hepatitis, often yellow fever)
Enlarge cells with intrnuclear inclusionsOwl Eyes- CMV
Eosinophilic Inclusion Bodies in cyoplasm of hippocampal and cerebellar nerve cellsNegri bodies of Rabies
Giant B Cells with bilobed nuclei with prominent inclusionsReed-Sternberg Cell (hodgkins lumphome
Glomerulue-like structure surrounding vesel in germ cellsSchiller-Duval (yolk sac tumor)
Hair on end (crew cut) appearance on X RayB Thalassemia, Sickle Cell Anemia (marrow expansion)
hCG ElevatedChoriocarcinoma, hydatidiform mole (occurs with and without embryo and multiple pregnancies)
Heart Nodules (granulomatous)Aschoff Bodies (rheumatic Fever)
Heterophile AbInfectious Mononucleiosis (EBV)
Hexagonal, double pointed, needle-like crystals in bronchial secretionsBronchial Ashthma (Charcot Leyden Crystals: Eosinophilic Granules)
High levels of D-dimersDVT PE, DIC
Hilar lymphadenopathy, peripheral granulomatous lesia in middle or lower lung lobes (can calcify)Ghon Complex (primary TB: Mycobacter bacilli)
Honey Comb Lung on XR or CTInterstitial Pulmonary Fibrosis
Hypercoagulability (leading to migrating DVTs and vasculitis)trousseaus syndrome (adenocarcinoma of the pancrease of lung)
Hypersegmented NeutrophilsMegaloblastic Anemia (b12 Deficiency: neurologic/ Folate: no neurologic
HTN, hypOkalemia, Metabolic AlkalosisConn Syndrome
Hypochromatic, Microcytic, AnemiaIron Def anemia, Lead Poisoning, Thalassemia (fetal hemoglobin)
Increases AFP Dating error, Ancephaly, Spina Bifida (neural tube defects)
Increase Uric AcidGout, Leschnyhan, tumor lysis syndrome, loop/thiazide diruetics
Intranuclear eosinophilic droplet-like bodiesCowdry Type A (HSV, CMV)
Iron Containing Nodules in alveolar septurmFerruginous bodies (asbesosis- increase mesothelioma)
Keratin Pearls on skin BiopsySquamous Cell Carcinoma
Large Lysosomal cesicles in phagocytes, immune deficiencyChediak Higashi (congenital failure of phagolysosome formation)
Lead Pipe appearance of Colon on barium enema X rayUlcerative Colitis (loss of haustra)
Linear appearance of IgG depo on Glomerular BMGood Pastures
Low serum ceruloplasminWilsons (hepatolenticular degeneration)
Lumpy Bumby apperance of glomeruli on immunoflorescencePSGN (immune complexes of IgG and C3b)
Lytic hole punched bone lesionsMutiple Myeloma
Mammary gland blue dommed cystFibrocystic change of the breast
Monoclonal Ab SpikeMultiple Myeloma (IgG/IgA), Monoclonal Gammopathy of undertermined significance MGUS - from aging, Waldenstrom (M protein- IgM) macroglobunemia, Primary Amyloidosis
Muscin filled cell with peripheral nucleiSignet Rings (gastric carcinoma)
Narrowing of bowel lumen on barium xrayString Sign Crohns Disease
Necrotizing Vasculitis (lungs) and necrotizing glomerulonephritisGranulomatosis with Polyangiitis (wegner; PR2 - ANCA/ cANCA) & Good Pasture syndrome (anti-basement membrane Ab)
Needle Shape, Negative Birefringent CrystalsGout (monosodium urate crystals)
Nodular hyaline deposits in glomeruliKimmestiel- Wilson Nodules (diabetic nephropath)
Novobiocin Sensitive Staph Epidermitis
Novobiocin ResistantStaph Saprophyticus
Nutmeg LiverChronic Passive Congestion of Liver due to right sided heart failure
Onion Skin periosteal reactionEwing Sarcoma (malignant round-cell tumor)
optopchin SensitiveStep Pneumo
optopchin resistantStrep Viridans
Periosteum raises from bone, creating triangular areaCodman's Triangle on X ray (osteosarcoma, ewing sarcoma, pyogenic osteomyelitis)
Podocyte fusion or effacement on EMMinimal Change Disease (child with nephrotic syndrome)
Polished Ivory-like appearance of bone at cartilage erosionebunation (Osteoarthritis - bony sclerosis)
Potein aggregates in neurons from hyperphosphorylation of tau proteinNeurofibrillary tangles (alzheimers) Pick Bodies (Pick disease)
Psuedopalisading tumore cells on brain biopsyGliobastoma multiforme
RBC Cast in UrineAcute glomerulonephritis
Rectangular, crystal-like cytoplasmic inclusions in Leydig CellsReinke Crystals (leydig tumor)
Renal epithelial casts in UrineActue Toxic/ Viral renal injury
Rhomboid crystal, positively bifefringentPseudogout (calcium pyrophosphate dihydrate crystals)
rib notchingCoarctation of the Aorta
Ring enhancing brain lesions in AidsToxoplasma gondii, CNS lymphoma
Sheets of medium sized lymphoid cells with scatterd pale, tingible body-laden macrophages (starry sky histology)Bukitt lymphoma (t[8:14] cmyc activation, associated with EBV; Black sky made up of malignant cells
Silver staining spherical aggregation of tau proteins in neuronsPick bodies (pick disease: progrssive dementia, changes in personality)
Soap Buddle in femur or tibia onx rayGiant Cell Tumor of Bone (benign)
Spike on basement membrane, dom-like subepithelia depositsMembranous glomerulonephritis (nephrotic syndrome)
Stacks of RBSRouleaux formation (high ESR, Multiple Myeloma)
Stippled Vaginal epithelial CellsClue Cells- Gardnerella Vaginalis
Tennis Racket- shaped cytoplasmic organelles EM in Langherhands CellsBirbeck Granuesl (langherhand cell histiocytosis or histiocytosis X: eosinophilic granuloma)
Thrombi made of white/red layersLines of Zhan (aterial thrombus, layers of platelets?RBCS)
Tram-track appearance of capillary loops of glomerular basement membranes on light microscopyMembranopoliferative Glomerulonephritis
Thumb Sign on lateral X rayEpiglottis Haemophillus Influenza
Thyroid Like Appearance in KidneyChronic Bacterial Pyelonephritis
Triglyceride accumulation in Liver Cell vacuolesFatty Liver Disease (alcoholics or metabolic syndrome)
Waxy Cell Casts with very low urine flowChronic End-stage renal Disease
WBC casts in UrineAcute Pyelonephritis
WBCS the look smudgedCLL (B CELLS)
Wire Loops glomerular capillary appearance on light microscopyLupus Nephropathy
Yellowish CSFXanthochromia - subarachnoid hemorrhage

Section 2

Question Answer
Owl EyesCMV, Hodgkins Lymphoma
Curschman SpiralAsthma- whorled Mucus
Koilocyte HPV
Homer Wright RosettesNeuroblatoma, Medulloblastoma, Retinoblastoma
Call Exner BodiesGranulosa Theca Cells
Orphan Annie Eyespapillary carcinoma of thyroid
Mallory BodyAlcoholic Liver Disease
Lewy BodyParkinsons
Councilman BodyYellow Fever -Toxic/Viral Hepatitis
Negri BodyRabies
Schiller DuvalYolk Sac Tumor
Aschoff BodiesRheumatic Fever
Charcot Leyden CrystalsBronchial Ashtma
Ghon ComplexPrimary TB
Trousseus SyndromeAdenocarcinoma of Pancrease or Lung
Megaloblastic Anemia WITH Neurologic SymptomsB12 Def
Megaloblastic Anemia W/O Neyrologic SymptomsFolat Def
Cowdry Type AHSV/CMV
Ferruginous BodiesAsbestosis
Loss of HaustraUlcerative Colits
hepatolenticular degnerationWilsons
IgG and c3 Immune Complex Deposition in GlomeruliPSGN
hole punched bone lesion/ IgA IgG SpikeMultiple Myeloma
Blue Domes CystFibrocystic Change of the Breast
M Protein= IgM spikeWaldenstrom Macroglobulinemia
Signet RingsGastric Carcinoma
String SignChron's Disease
monosodium urate crystalsGout
Kimmelstiel Wilson NodulesDiabetic Nephropathy
Codman's Triangle Osteosarcoma
Neurofibrillary Tangles Alzheimers
Pick BodiesPick Disease
Psamomma Bodies Meningiomas, Papillary thyroid carcinoma, mesothelioma, papillary serous carcinoma of the endometrium and ovary
Reinke CrystalsLeydig Tumor
Calcium pyrophosphate dihydrate crystalsPseudogout
Starry Sky t[8:14] c-myc activationBurkitt Lymphoma
Soap BubbleOsteoCLastoma
Spikes and Domes Membranous Glomerulonephritis
effacement of podocytesMinimal Change Disease
Onion SkinEwings
Apple CoreLS Colorectal Cancer
Bamboo SpineAnkylosing Spondylitis
Boot ShapeTeratology of Fallot
Brown Bone TumorsHyperparathyroidism/ Oosteitis Fibrosa Cystica
Chocolate CystEndometriosis of Ovary
Hair on EndB thalassemia/ Sickle Cell
Honey Comb LungInterstitial Pulmonary Fibrosis
Lead Pipe ColonUcerative Colitis
Nut Meg LiverRight Heart Failure
RouleauxMultiple Myeloma
Clue CellsGardnerella Vaginalis
Birbeck GranulesLangherhand Histiocytosis
Tennis RacketsBirbeck Granules
Lines of ZhanArterial Thrombus
Tram TrackMembranopoliferative Glomerulonephritis
Thumb Signepiglotitis
Fatty Liver DiseaseAlcholic/ Metabolic Syndrome
Smudge CellsB Cells
Wire-Loops Lupus
XanthochromiaSubarachnoid Hemorrhage
WBC CastAcute Pyelonephritis
Waxy CastChronic End Stage-Renal Disease

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